Trim11 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comTrim11 ELISA Kit for Rat(Rattus norvegicus)

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Trim11 (Gene name),

E3 ubiquitin-protein ligase TRIM11 (Protein name ), TRI11_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Trim11;

Protein name:

E3 ubiquitin-protein ligase TRIM11;

Alternative:

Tripartite motif-containing protein 11;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Binds cytoplasmic tail of integrin alpha-1. Interacts with MED15/ARC105; this interaction leads to MED15 ubiquitination and proteasomal degradation. Interacts with the HN peptide. Interacts with PHOX2B. Interacts with PAX6.

Function:

E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation. May contribute to the innate restriction of retroviruses.

Subcellular Location:

Cytoplasm Nucleus In the nucleus, colocalizes with PAX6.

Protein Attributes:

Sequence length:

467

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

467:

MTICRLIGVS | GDTLGPQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00622

Pfam:

PF13765

UniGene:

Rn.9308

String:

B1H278

STRING:

10116.ENSRNOP00000003902

Uniprot:

B1H278

FOR

ELISA Kit for Rat E3 ubiquitin-protein ligase TRIM11

CLIA Kit for Rat E3 ubiquitin-protein ligase TRIM11

Polyclonal Antibody for Rat E3 ubiquitin-protein ligase TRIM11

Monoclonal Antibody for Rat E3 ubiquitin-protein ligase TRIM11

Protein for Rat E3 ubiquitin-protein ligase TRIM11

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Placenta.

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