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Index > Protein center > TRIM3(Gene name) > Human
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  • TRIM3 (Gene name),
  • Tripartite motif-containing protein 3 (Protein name ),  TRIM3_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    TRIM3(BERP;RNF22;RNF97);
    Protein name:
    Tripartite motif-containing protein 3;
    Alternative:
    RING finger protein 22;Brain-expressed RING finger protein;RING finger protein 97;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Associates with myosin-Vb (MYO5B) and alpha-actinin-4 (ACTN4) (By similarity). Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3. Interacts with ZFYVE28/LST2.
    Function:
    Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
    Subcellular Location:
    Cytoplasm Early endosome
    Protein Attributes:
    Sequence length:
    744
    Sequence:
    50:
    MAKREDSPGP | EVQPMDKQFL | VCSICLDRYQ | CPKVLPCLHT | FCERCLQNYI | 
    100:
    PAQSLTLSCP | VCRQTSILPE | QGVSALQNNF | FISSLMEAMQ | QAPDGAHDPE | 
    150:
    DPHPLSVVAG | RPLSCPNHEG | KTMEFYCEAC | ETAMCGECRA | GEHREHGTVL | 
    200:
    LRDVVEQHKA | ALQRQLEAVR | GRLPQLSAAI | ALVGGISQQL | QERKAEALAQ | 
    250:
    ISAAFEDLEQ | ALQQRKQALV | SDLETICGAK | QKVLQSQLDT | LRQGQEHIGS | 
    300:
    SCSFAEQALR | LGSAPEVLLV | RKHMRERLAA | LAAQAFPERP | HENAQLELVL | 
    350:
    EVDGLRRSVL | NLGALLTTSA | TAHETVATGE | GLRQALVGQP | ASLTVTTKDK | 
    400:
    DGRLVRTGSA | ELRAEITGPD | GTRLPVPVVD | HKNGTYELVY | TARTEGELLL | 
    450:
    SVLLYGQPVR | GSPFRVRALR | PGDLPPSPDD | VKRRVKSPGG | PGSHVRQKAV | 
    500:
    RRPSSMYSTG | GKRKDNPIED | ELVFRVGSRG | REKGEFTNLQ | GVSAASSGRI | 
    550:
    VVADSNNQCI | QVFSNEGQFK | FRFGVRGRSP | GQLQRPTGVA | VDTNGDIIVA | 
    600:
    DYDNRWVSIF | SPEGKFKTKI | GAGRLMGPKG | VAVDRNGHII | VVDNKSCCVF | 
    650:
    TFQPNGKLVG | RFGGRGATDR | HFAGPHFVAV | NNKNEIVVTD | FHNHSVKVYS | 
    700:
    ADGEFLFKFG | SHGEGNGQFN | APTGVAVDSN | GNIIVADWGN | SRIQVFDSSG | 
    744:
    SFLSYINTSA | EPLYGPQGLA | LTSDGHVVVA | DAGNHCFKAY | RYLQ
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    MIM:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tripartite motif-containing protein 3
    Cat.:
    E9579m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Tripartite motif-containing protein 3
    Cat.:
    E9579r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Tripartite motif-containing protein 3
    Cat.:
    E9579h
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Tripartite motif-containing protein 3
    Cat.:
    U9579m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tripartite motif-containing protein 3
    Cat.:
    U9579h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tripartite motif-containing protein 3
    Cat.:
    U9579r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Tripartite motif-containing protein 3
    Cat.:
    P9579Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tripartite motif-containing protein 3
    Polyclonal Antibody for Human Tripartite motif-containing protein 3
    Cat.:
    P9579Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Tripartite motif-containing protein 3
    Monoclonal Antibody for Human Tripartite motif-containing protein 3
    Monoclonal Antibody for Human Tripartite motif-containing protein 3
    Protein for Human Tripartite motif-containing protein 3
    Protein for Human Tripartite motif-containing protein 3
    Protein for Human Tripartite motif-containing protein 3

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    Linearity
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    References
    1. 1.
      "Cloning and characterization of a gene (RNF22) encoding a novel brain expressed ring finger protein (BERP) that maps to human chromosome 11p15.5."
      El-Husseini A.E.-D. , Fretier P. , Vincent S.R.
      Genomics71:363-367(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA)
      tissue: Brain.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS ALPHA; BETA AND GAMMA)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS ALPHA AND 4)
      tissue: Brain.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA)
      tissue: Cervix.
    7. 7.
      "CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling."
      Yan Q. , Sun W. , Kujala P. , Lotfi Y. , Vida T.A. , Bean A.J.
      Mol. Biol. Cell16:2470-2482(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE CART COMPLEX;SUBCELLULAR LOCATION
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    10. 10.
      "Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling."
      Mosesson Y. , Chetrit D. , Schley L. , Berghoff J. , Ziv T. , Carvalho S. , Milanezi F. , Admon A. , Schmitt F. , Ehrlich M. , Yarden Y.
      Dev. Cell16:687-698(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZFYVE28
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