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Index > Protein center > TRPC4(Gene name) > Bovine
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  • TRPC4 (Gene name),
  • Short transient receptor potential channel 4 (Protein name ),  TRPC4_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TRPC4;
    Protein name:
    Short transient receptor potential channel 4(TrpC4);
    Alternative:
    Capacitative calcium entry channel 1(CCE1);
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homotetramer and heterotetramer with TRPC1 and/or TRPC5 (By similarity). Isoform alpha associates with inositol-1,4,5-triphosphate receptor (ITPR). Interacts with (via the PDZ-binding domain) with NHERF (By similarity). Interacts with MX1 and RNF24 (By similarity). Interacts (via CIRB domain) with SESTD1 (via the spectrin 1 repeat) (By similarity). Interacts with CDH5 and CTNNB1 (By similarity). Interacts (via protein 4.1-binding domain) with EPB41L2 (By similarity). Interacts with TRPC4AP.
    Function:
    Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion. Acts as a cell-cell contact-dependent endothelial calcium entry channel.
    Subcellular Location:
    Membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    979
    Sequence:
    50:
    MAQFYYKRNV | NAPYRDRIPL | RIVRAESELS | PSEKAYLNAV | EKGDYASVKK | 
    100:
    SLEEAEIYFK | ININCIDPLG | RTALLIAIEN | ENLELIELLL | SFNVYVGDAL | 
    150:
    LHAIRKEVVG | AVELLLNHKK | PSGEKQVPPI | LLDKQFSEFT | PDITPIILAA | 
    200:
    HTNNYEIIKL | LVQKGVSVPR | PHEVRCNCVE | CVSSSDVDSL | RHSRSRLNIY | 
    250:
    KALASPSLIA | LSSEDPFLTA | FQLSWELQEL | SKVENEFKSE | YEELSRQCKQ | 
    300:
    FAKDLLDQTR | SSRELEIILN | YRDDNSLLEE | QSGNDLARLK | LAIKYRQKEF | 
    350:
    VAQPNCQQLL | ASRWYDEFPG | WRRRHWAVKM | VTCFIVGLLF | PVFSVCYLIA | 
    400:
    PKSPLGLFIR | KPFIKFICHT | ASYLTFLFLL | LLASQHIDRS | DLNRQGPPPT | 
    450:
    IVEWMILPWV | LGFIWGEIKQ | MWDGGLQDYI | HDWWNLMDFV | MNSLYLATIS | 
    500:
    LKIVAFVKYS | ALNPRESWDM | WHPTLVAEAL | FAIANIFSSL | RLISLFTANS | 
    550:
    HLGPLQISLG | RMLLDILKFL | FIYCLVLLAF | ANGLNQLYFY | YEETKGLSCK | 
    600:
    GIRCEKQNNA | FSTLFETLQS | LFWSIFGLIN | LYVTNVKAQH | EFTEFVGATM | 
    650:
    FGTYNVISLV | VLLNMLIAMM | NNSYQLIADH | ADIEWKFART | KLWMSYFEEG | 
    700:
    GTLPTPFNVI | PSPKSLWYLI | KWIWTHLCKK | KMRRKPESFG | TIGRRAADNL | 
    750:
    RRHHQYQEVM | RNLVKRYVAA | MIRDAKTEEG | LTEENFKELK | QDISSFRFEV | 
    800:
    LGLLRGSKLS | TVQSAQGTKE | SSNSADSDEK | SDNEGSSKDK | KKNFSLFDLT | 
    850:
    TLIHPRSAAI | AAERHTISNG | SALVVQEPPR | EKQRKVNFVT | DIRHFGLFHR | 
    900:
    RSKQHAAAEQ | NANQIFSVSE | GVARQQAEGP | LERSIQLESR | TLASRGDLNI | 
    950:
    PGLSEQCILV | DHRERNTDSL | GVQVSKRVCS | FKSEKVVVED | TVPIIPKEKK | 
    979:
    HAKEEDSSAD | YDANLTDTIT | HEDYVTTRL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine TrpC4
    ELISA Kit for Bovine TrpC4
    ELISA Kit for Bovine TrpC4
    ELISA Kit for Bovine TrpC4
    CLIA Kit for Bovine TrpC4
    CLIA Kit for Bovine TrpC4
    CLIA Kit for Bovine TrpC4
    CLIA Kit for Bovine TrpC4
    Polyclonal Antibody for Bovine TrpC4
    Polyclonal Antibody for Bovine TrpC4
    Polyclonal Antibody for Bovine TrpC4
    Polyclonal Antibody for Bovine TrpC4
    Monoclonal Antibody for Bovine TrpC4
    Monoclonal Antibody for Bovine TrpC4
    Monoclonal Antibody for Bovine TrpC4
    Monoclonal Antibody for Bovine TrpC4
    Protein for Bovine TrpC4
    Protein for Bovine TrpC4
    Protein for Bovine TrpC4
    Protein for Bovine TrpC4

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    References
    1. 1.
      "A mammalian capacitative calcium entry channel homologous to Drosophila TRP and TRPL."
      Philipp S. , Cavalie A. , Freichel M. , Wissenbach U. , Zimmer S. , Trost C. , Marquart A. , Murakami M. , Flockerzi V.
      EMBO J.15:6166-6171(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA)
      tissue: Adrenal gland.
      tissue: Retina.
    2. 2.
      "Alternative splicing and tissue specific expression of the 5' truncated bCCE 1 variant bCCE 1delta514."
      Freichel M. , Wissenbach U. , Philipp S. , Flockerzi V.
      FEBS Lett.422:354-358(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM BETA)
      tissue: Adrenal gland.
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