Trpc5 ELISA Kit for Mouse(Mus musculus) | EIAab.comTrpc5 ELISA Kit for Mouse(Mus musculus)

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Trpc5 (Gene name),

Short transient receptor potential channel 5 (Protein name ), TRPC5_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Trpc5(Trp5;Trrp5);

Protein name:

Short transient receptor potential channel 5(TrpC5);

Alternative:

Transient receptor protein 5(TRP-5;mTRP5);Capacitative calcium entry channel 2(CCE2);Trp-related protein 5;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homotetramer and heterotetramer with TRPC1 and/or TRPC4 (By similarity). Interacts (via C-terminus) with CABP1. Interacts with NHERF (By similarity). Interacts with MX1 and RNF24 (By similarity). Interacts with SESTD1 (via the spectrin 1 repeat) (By similarity). Interacts with TRPC4AP.

Function:

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

975

Sequence:

50:

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650:

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750:

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950:

975:

TWGEACDLLM | HKWGDGQEEQ | VTTRL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:22067

UniGene:

Mm.328378

String:

Q9QX29

SMR:

Q9QX29

Pfam:

PF00023

Pfam:

PF12796

Uniprot:

Q9QX29

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ELISA Kit for Mouse TrpC5

CLIA Kit for Mouse TrpC5

Polyclonal Antibody for Mouse TrpC5

Monoclonal Antibody for Mouse TrpC5

Protein for Mouse TrpC5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Molecular cloning and functional characterization of a novel receptor-activated TRP Ca2+ channel from mouse brain."
Okada T. , Shimizu S. , Wakamori M. , Maeda A. , Kurosaki T. , Takada N. , Imoto K. , Mori Y.
J. Biol. Chem.273:10279-10287(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"Molecular cloning and functional expression of mouse TRP5."
Zhu X. , Peyton M. , Boulay B. , Birnbaumer B.
Submitted (1998-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF."
Tang Y. , Tang J. , Chen Z. , Trost C. , Flockerzi V. , Li M. , Ramesh V. , Zhu M.X.
J. Biol. Chem.275:37559-37564(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"A novel capacitative calcium entry channel expressed in excitable cells."
Philipp S. , Hambrecht J. , Braslavski L. , Schroth G. , Freichel M. , Murakami M. , Cavalie A. , Flockerzi V.
EMBO J.17:4274-4282(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-966;TISSUE SPECIFICITY
tissue: Brain.
5.

Lubec G. , Sunyer B. , Chen W.-Q.
Submitted (2009-01) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 354-361;IDENTIFICATION BY MASS SPECTROMETRY
strain: OF1.
tissue: Hippocampus.
6.

"trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry."
Zhu X. , Jiang M. , Peyton M. , Boulay G. , Hurst R. , Stefani E. , Birnbaumer L.
Cell85:661-671(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 515-637
7.

"Inhibition of TRPC5 channels by Ca2+-binding protein 1 in Xenopus oocytes."
Kinoshita-Kawada M. , Tang J. , Xiao R. , Kaneko S. , Foskett J.K. , Zhu M.X.
Pflugers Arch.450:345-354(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CABP1
8.

"TRUSS, TNF-R1, and TRPC ion channels synergistically reverse endoplasmic reticulum Ca2+ storage reduction in response to m1 muscarinic acetylcholine receptor signaling."
Mace K.E. , Lussier M.P. , Boulay G. , Terry-Powers J.L. , Parfrey H. , Perraud A.L. , Riches D.W.H.
J. Cell. Physiol.225:444-453(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRPC4AP

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