Tpsb2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comTpsb2 ELISA Kit for Rat(Rattus norvegicus)

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Tpsb2 (Gene name),

Tryptase beta-2 (Protein name ), TRYB2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Tpsb2(Mcp6;Mcpt6);

Protein name:

Tryptase beta-2(Tryptase-2);

Alternative:

Mast cell protease 6(rMCP-6);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homotetramer. The active tetramer is converted to inactive monomers at neutral and acidic pH in the absence of heparin. Low concentrations of inactive monomers become active monomers at pH 6.0 in the presence of heparin. When the concentration of active monomers is higher, they convert to active monomers and then to active tetramers. These monomers are active and functionally distinct from the tetrameric enzyme. In contrast to the hidden active sites in the tetrameric form, the active site of the monomeric form is accessible for macromolecular proteins and inhibitors eg: fibrinogen which is a substrate for the monomeric but not for the tetrameric form. The monomeric form forms a complex with SERPINB6.

Function:

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Has an immunoprotective role during bacterial infection. Required to efficiently combat K.pneumoniae infection.

Subcellular Location:

Secreted Released from the secretory granules upon mast cell activation.

Protein Attributes:

Sequence length:

274

Sequence:

50:

100:

150:

200:

250:

274:

NRPGIYTRVT | YYLDWIHRYV | PQRS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P50343

Pfam:

PF00089

STRING:

10116.ENSRNOP00000025220

KEGG:

rno:29268

UniGene:

Rn.10183

Uniprot:

P50343

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ELISA Kit for Rat Tryptase-2

Cat.:

E0258h

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96T

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ELISA Kit for Rat Tryptase-2

Cat.:

E0258m

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96T

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ELISA Kit for Rat Tryptase-2

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E0258r

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CLIA Kit for Rat Tryptase-2

Cat.:

U0258m

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96T

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CLIA Kit for Rat Tryptase-2

Cat.:

U0258h

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96T

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CLIA Kit for Rat Tryptase-2

Cat.:

U0258r

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Packing:

96T

Polyclonal Antibody for Rat Tryptase-2

Cat.:

P0258Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Tryptase-2

Cat.:

P0258Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Tryptase-2

Cat.:

P0258Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Tryptase-2

Protein for Rat Tryptase-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"cDNA sequencing and expression of rat mast cell tryptase."
Ide H. , Itoh H. , Tomita M. , Murakumo Y. , Kobayashi T. , Maruyama H. , Osada Y. , Nawa Y.
J. Biochem.118:210-215(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Peritoneal mast cell.
2.

"Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations."
Lutzelschwab C. , Pejler G. , Aveskogh M. , Hellman L.
J. Exp. Med.185:13-29(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
tissue: Peritoneal mast cell.

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