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Index > Protein center > TTPA(Gene name) > Human
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  • TTPA (Gene name),
  • Alpha-tocopherol transfer protein (Protein name ),  TTPA_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TTPA(TPP1);
    Protein name:
    Alpha-tocopherol transfer protein(Alpha-TTP);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Binds alpha-tocopherol and enhances its transfer between separate membranes.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    278
    Sequence:
    50:
    MAEARSQPSA | GPQLNALPDH | SPLLQPGLAA | LRRRAREAGV | PLAPLPLTDS | 
    100:
    FLLRFLRARD | FDLDLAWRLL | KNYYKWRAEC | PEISADLHPR | SIIGLLKAGY | 
    150:
    HGVLRSRDPT | GSKVLIYRIA | HWDPKVFTAY | DVFRVSLITS | ELIVQEVETQ | 
    200:
    RNGIKAIFDL | EGWQFSHAFQ | ITPSVAKKIA | AVLTDSFPLK | VRGIHLINEP | 
    250:
    VIFHAVFSMI | KPFLTEKIKE | RIHMHGNNYK | QSLLQHFPDI | LPLEYGGEEF | 
    278:
    SMEDICQEWT | NFIMKSEDYL | SSISESIQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    MIM:
    Pfam:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Alpha-TTP
    Cat.:
    E13001h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Alpha-TTP
    Cat.:
    E13001r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Alpha-TTP
    Cat.:
    E13001m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Alpha-TTP
    MSDS:
    Please sign in first.
    CLIA Kit for Human Alpha-TTP
    Cat.:
    U13001m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Alpha-TTP
    Cat.:
    U13001h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Alpha-TTP
    Polyclonal Antibody for Human Alpha-TTP
    Polyclonal Antibody for Human Alpha-TTP
    Monoclonal Antibody for Human Alpha-TTP
    Monoclonal Antibody for Human Alpha-TTP
    Monoclonal Antibody for Human Alpha-TTP
    Protein for Human Alpha-TTP
    Protein for Human Alpha-TTP
    Protein for Human Alpha-TTP

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Human alpha-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization."
      Arita M. , Sato Y. , Miyata A. , Tanabe T. , Takahashi E. , Kayden H.J. , Arai H. , Inoue K.
      Biochem. J.306:437-443(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    2. 2.
      "Human alpha-tocopherol transfer protein: gene structure and mutations in familial vitamin E deficiency."
      Hentati A. , Deng H.-X. , Hung W.-Y. , Nayer M. , Ahmed M.S. , He X. , Tim R. , Stumpf D.A. , Siddique T.
      Ann. Neurol.39:295-300(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT AVED HIS-192
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
    4. 4.
      "Ataxia with isolated vitamin E deficiency: heterogeneity of mutations and phenotypic variability in a large number of families."
      Cavalier L. , Ouahchi K. , Kayden H.J. , Di Donato S. , Reutenauer L. , Mandel J.-L. , Koenig M.
      Am. J. Hum. Genet.62:301-310(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-119;VARIANTS AVED TRP-59; THR-120; LYS-141 AND TRP-221
    5. 5.
      "Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein."
      Ouahchi K. , Arita M. , Kayden H. , Hentati F. , Ben-Hamida M. , Sokol R. , Arai H. , Inoue K. , Mandel J.-L. , Koenig M.
      Nat. Genet.9:141-145(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 170-180 AND 246-265;DISEASE
    6. 6.
      "The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein."
      Meier R. , Tomizaki T. , Schulze-Briese C. , Baumann U. , Stocker A.
      J. Mol. Biol.331:725-734(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS)
    7. 7.
      "Crystal structure of human alpha-tocopherol transfer protein bound to its ligand: implications for ataxia with vitamin E deficiency."
      Min K.C. , Kovall R.A. , Hendrickson W.A.
      Proc. Natl. Acad. Sci. U.S.A.100:14713-14718(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF 21-278
    8. 8.
      "Adult-onset spinocerebellar dysfunction caused by a mutation in the gene for the alpha-tocopherol-transfer protein."
      Gotoda T. , Arita M. , Arai H. , Inoue K. , Yokota T. , Fukuo Y. , Yazaki Y. , Yamada N.
      N. Engl. J. Med.333:1313-1318(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AVED GLN-101
    9. 9.
      "Molecular determinants of heritable vitamin E deficiency."
      Morley S. , Panagabko C. , Shineman D. , Mani B. , Stocker A. , Atkinson J. , Manor D.
      Biochemistry43:4143-4149(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANTS AVED TRP-59; GLN-101; THR-120; LYS-141; HIS-192 AND TRP-221
    10. 10.
      "Ataxia with isolated vitamin E deficiency: neurological phenotype, clinical follow-up and novel mutations in TTPA gene in Italian families."
      Mariotti C. , Gellera C. , Rimoldi M. , Mineri R. , Uziel G. , Zorzi G. , Pareyson D. , Piccolo G. , Gambi D. , Piacentini S. , Squitieri F. , Capra R. , Castellotti B. , Di Donato S.
      Neurol. Sci.25:130-137(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AVED ARG-246
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