Gene name:
UBE2D1 (SFT;UBC5A;UBCH5;UBCH5A) ;
Protein name:
Ubiquitin-conjugating enzyme E2 D1 ;
Alternative:
UBC4/5 homolog ;Stimulator of Fe transport (SFT) ;Ubiquitin carrier protein D1 ;UbcH5 ;Ubiquitin-conjugating enzyme E2-17 kDa 1 ;Ubiquitin-conjugating enzyme E2(17)KB 1 ;Ubiquitin-protein ligase D1 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Component of a E3 ubiquitin ligase complex containing UBE2D1, SIAH1, CACYBP/SIP, SKP1, APC and TBL1X. Interacts with RNF11.
Function:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MALKRIQKEL | SDLQRDPPAH | CSAGPVGDDL | FHWQATIMGP | PDSAYQGGVF |
100:
FLTVHFPTDY | PFKPPKIAFT | TKIYHPNINS | NGSICLDILR | SQWSPALTVS |
147:
KVLLSICSLL | CDPNPDDPLV | PDIAQIYKSD | KEKYNRHARE | WTQKYAM
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Bovine
Human
Rat
ELISA Kit for Human Ubiquitin-conjugating enzyme E2 D1
ELISA Kit for Human Ubiquitin-conjugating enzyme E2 D1
ELISA Kit for Human Ubiquitin-conjugating enzyme E2 D1
ELISA Kit for Human Ubiquitin-conjugating enzyme E2 D1
CLIA Kit for Human Ubiquitin-conjugating enzyme E2 D1
CLIA Kit for Human Ubiquitin-conjugating enzyme E2 D1
CLIA Kit for Human Ubiquitin-conjugating enzyme E2 D1
CLIA Kit for Human Ubiquitin-conjugating enzyme E2 D1
Polyclonal Antibody for Human Ubiquitin-conjugating enzyme E2 D1
Polyclonal Antibody for Human Ubiquitin-conjugating enzyme E2 D1
Polyclonal Antibody for Human Ubiquitin-conjugating enzyme E2 D1
Polyclonal Antibody for Human Ubiquitin-conjugating enzyme E2 D1
Monoclonal Antibody for Human Ubiquitin-conjugating enzyme E2 D1
Monoclonal Antibody for Human Ubiquitin-conjugating enzyme E2 D1
Monoclonal Antibody for Human Ubiquitin-conjugating enzyme E2 D1
Monoclonal Antibody for Human Ubiquitin-conjugating enzyme E2 D1
Protein for Human Ubiquitin-conjugating enzyme E2 D1
Protein for Human Ubiquitin-conjugating enzyme E2 D1
Protein for Human Ubiquitin-conjugating enzyme E2 D1
Protein for Human Ubiquitin-conjugating enzyme E2 D1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];TISSUE SPECIFICITY
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[
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Skeletal muscle .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
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Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Bone marrow .
tissue :
Skin .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 134-147;TISSUE SPECIFICITY
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ERRATUM
10.
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Cited for : SUBUNIT OF A COMPLEX WITH SIAH1; CACYBP; SKP1; APC AND TBL1X
11.
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Cited for : INTERACTION WITH RNF11
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) IN COMPLEX WITH MYLIP