Ube2d2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comUbe2d2 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Ube2d2(Gene name) > Rat

Ube2d2 (Gene name),

Ubiquitin-conjugating enzyme E2 D2 (Protein name ), UB2D2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ube2d2(Ubc4;Ubch4;Ubch5b);

Protein name:

Ubiquitin-conjugating enzyme E2 D2;

Alternative:

Ubiquitin-conjugating enzyme E2(17)KB 2;Ubiquitin carrier protein D2;Ubiquitin-protein ligase D2;Ubiquitin-conjugating enzyme E2-17 kDa 2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex and with E3 ubiquitin-protein ligase PJA2 (By similarity). Interacts with PDZRN3 (By similarity). Interacts with CNOT4 (via RING domain).

Function:

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3 (By similarity). Mediates ubiquitination of PEX5.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

147

Sequence:

50:

100:

147:

KVLLSICSLL | CDPNPDDPLV | PEIARIYKTD | REKYNRIARE | WTQKYAM

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P62839

KEGG:

rno:641452

String:

P62839

UniGene:

Rn.7390

Pfam:

PF00179

Uniprot:

P62839

FOR

ELISA Kit for Rat Ubiquitin-conjugating enzyme E2 D2

CLIA Kit for Rat Ubiquitin-conjugating enzyme E2 D2

Polyclonal Antibody for Rat Ubiquitin-conjugating enzyme E2 D2

Monoclonal Antibody for Rat Ubiquitin-conjugating enzyme E2 D2

Protein for Rat Ubiquitin-conjugating enzyme E2 D2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning, expression and characterization of a ubiquitin conjugation enzyme (E2(17)kB) highly expressed in rat testis."
Wing S.S. , Jain P.
Biochem. J.305:125-132(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
tissue: Testis.
2.

"Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor."
Grou C.P. , Carvalho A.F. , Pinto M.P. , Wiese S. , Piechura H. , Meyer H.E. , Warscheid B. , Sa-Miranda C. , Azevedo J.E.
J. Biol. Chem.283:14190-14197(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION BY MASS SPECTROMETRY

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