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Index > Protein center > UBE2I(Gene name) > Human
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  • UBE2I (Gene name),
  • SUMO-conjugating enzyme UBC9 (Protein name ),  UBC9_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    UBE2I(UBC9;UBCE9);
    Protein name:
    SUMO-conjugating enzyme UBC9;
    Alternative:
    Ubiquitin carrier protein 9;SUMO-protein ligase;Ubiquitin-conjugating enzyme E2 I;Ubiquitin carrier protein I;p18;Ubiquitin-protein ligase I;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with HIPK1, HIPK2, PPM1J, RASD2 and TCF3 Interacts with NR2C1; the interaction promotes its sumoylation (By similarity). Forms a tight complex with RANGAP1 and RANBP2. Interacts with SIAH1 and PARP. Interacts with various transcription factors such as TFAP2A, TFAP2B, TFAP2C, AR, ETS1 and SOX4. Interacts with RWDD3; the interaction enhances the sumoylation of a number of proteins such as HIF1A and I-kappa-B. Interacts with DNMT1. Interacts with FOXL2. Forms a complex with SENP6 and UBE2I in response to UV irradiation. Interacts with human herpesvirus 6 IE2. Interacts with human adenovirus early E1A protein; this interaction interferes with polysumoylation (Probable). Interacts with DNM1l (via its GTPase and B domains); the interaction promotes sumoylation of DNM1L, mainly in its B domain. Interacts with PML-RARA oncoprotein (via the coiled-colied domain); the interaction is required for sumoylation of the PML-RARA oncoprotein. Interacts with IPO13. Interacts with NFATC2IP; this inhibits formation of poly-SUMO chains.
    Function:
    Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation.
    Subcellular Location:
    Nucleus Cytoplasm Mainly nuclear. In spermatocytes, localizes in synaptonemal complexes. Recruited by BCL11A into the nuclear body.
    Protein Attributes:
    Sequence length:
    158
    Sequence:
    50:
    MSGIALSRLA | QERKAWRKDH | PFGFVAVPTK | NPDGTMNLMN | WECAIPGKKG | 
    100:
    TPWEGGLFKL | RMLFKDDYPS | SPPKCKFEPP | LFHPNVYPSG | TVCLSILEED | 
    150:
    KDWRPAITIK | QILLGIQELL | NEPNIQDPAQ | AEAYTIYCQN | RVEYEKRVRA | 
    158:
    QAKKFAPS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    SMR:
    KEGG:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human SUMO-conjugating enzyme UBC9
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    ELISA Kit for Human SUMO-conjugating enzyme UBC9
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    E11134h
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    ELISA Kit for Human SUMO-conjugating enzyme UBC9
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    ELISA Kit for Human SUMO-conjugating enzyme UBC9
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    E11134r
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    CLIA Kit for Human SUMO-conjugating enzyme UBC9
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    U11134h
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    CLIA Kit for Human SUMO-conjugating enzyme UBC9
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    CLIA Kit for Human SUMO-conjugating enzyme UBC9
    Cat.:
    U11134m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human SUMO-conjugating enzyme UBC9
    Cat.:
    U11134r
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    MSDS:
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    Packing:
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    Polyclonal Antibody for Human SUMO-conjugating enzyme UBC9
    Cat.:
    P11134Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human SUMO-conjugating enzyme UBC9
    Polyclonal Antibody for Human SUMO-conjugating enzyme UBC9
    Polyclonal Antibody for Human SUMO-conjugating enzyme UBC9
    Monoclonal Antibody for Human SUMO-conjugating enzyme UBC9
    Monoclonal Antibody for Human SUMO-conjugating enzyme UBC9
    Monoclonal Antibody for Human SUMO-conjugating enzyme UBC9
    Monoclonal Antibody for Human SUMO-conjugating enzyme UBC9
    Protein for Human SUMO-conjugating enzyme UBC9
    Protein for Human SUMO-conjugating enzyme UBC9
    Protein for Human SUMO-conjugating enzyme UBC9
    Protein for Human SUMO-conjugating enzyme UBC9

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Identification of the structural and functional human homolog of the yeast ubiquitin conjugating enzyme UBC9."
      Yasugi T. , Howley P.M.
      Nucleic Acids Res.24:2005-2010(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
    2. 2.
      "Assignment of the gene for a ubiquitin-conjugating enzyme (UBE2I) to human chromosome band 16p13.3 by in situ hybridization."
      Tachibana M. , Iwata N. , Watanabe A. , Nobukuni Y. , Ploplis B. , Kajigaya S.
      Cytogenet. Cell Genet.75:222-223(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Cloning, expression, and mapping of UBE2I, a novel gene encoding a human homologue of yeast ubiquitin-conjugating enzymes which are critical for regulating the cell cycle."
      Watanabe T.K. , Fujiwara T. , Kawai A. , Shimizu F. , Takami S. , Hirano H. , Okuno S. , Ozaki K. , Takeda S. , Shimada Y. , Nagata M. , Takaichi A. , Takahashi E. , Nakamura Y. , Shin S.
      Cytogenet. Cell Genet.72:86-89(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Fetal brain.
    4. 4.
      "Poly(ADP-ribose) polymerase interacts with a novel human ubiquitin conjugating enzyme: hUbc9."
      Masson M. , Menissier-de Murcia J. , Mattei M.-G. , de Murcia G.M. , Niedergang C.P.
      Gene190:287-296(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH PARP
    5. 5.
      "Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes."
      Kovalenko O.V. , Plug A.W. , Haaf T. , Gonda D.K. , Ashley T. , Ward D.C. , Radding C.M. , Golub E.I.
      Proc. Natl. Acad. Sci. U.S.A.93:2958-2963(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
    6. 6.
      "Two-hybrid interaction of a human UBC9 homolog with centromere proteins of Saccharomyces cerevisiae."
      Jiang W. , Koltin Y.
      Mol. Gen. Genet.251:153-160(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    7. 7.
      "Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9."
      Wang Z.-Y. , Qiu Q. , Seufert W. , Taguchi T. , Testa J.R. , Whitmore S.A. , Callen D.F. , Welsh D. , Shenk T. , Deuel T.F.
      J. Biol. Chem.271:24811-24816(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Placenta.
    8. 8.
      Shen Z.
      Submitted (1995-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    9. 9.
      "Modulation of ETS-1 transcriptional activity by huUBC9, a ubiquitin-conjugating enzyme."
      Hahn S.L. , Criqui-Filipe P. , Wasylyk B.
      Oncogene15:1489-1495(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    10. 10.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2004-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    11. 11.
      Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S. , Ohara O. , Nagase T. , Kikuno R.F.
      Submitted (2005-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    12. 12.
      "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16."
      Daniels R.J. , Peden J.F. , Lloyd C. , Horsley S.W. , Clark K. , Tufarelli C. , Kearney L. , Buckle V.J. , Doggett N.A. , Flint J. , Higgs D.R.
      Hum. Mol. Genet.10:339-352(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    14. 14.
      "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
      Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    15. 15.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    16. 16.
      "mUBC9, a novel adenovirus E1A-interacting protein that complements a yeast cell cycle defect."
      Hateboer G. , Hijmans E.M. , Nooij J.B.D. , Schlenker S. , Jentsch S. , Bernards R.
      J. Biol. Chem.271:25906-25911(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ADENOVIRUS E1A
    17. 17.
      "Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway."
      Hu G. , Zhang S. , Vidal M. , Baer J.L. , Xu T. , Fearon E.R.
      Genes Dev.11:2701-2714(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SIAH1
    18. 18.
      "Ubc9 interacts with the androgen receptor and activates receptor-dependent transcription."
      Poukka H. , Aarnisalo P. , Karvonen U. , Palvimo J.J. , Jaenne O.A.
      J. Biol. Chem.274:19441-19446(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AR
    19. 19.
      "Association of FHIT (fragile histidine triad), a candidate tumour suppressor gene, with the ubiquitin-conjugating enzyme hUBC9."
      Shi Y. , Zou M. , Farid N.R. , Paterson M.C.
      Biochem. J.352:443-448(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FHIT
    20. 20.
      "Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9."
      Tatham M.H. , Jaffray E. , Vaughan O.A. , Desterro J.M.P. , Botting C.H. , Naismith J.H. , Hay R.T.
      J. Biol. Chem.276:35368-35374(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    21. 21.
      "Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo."
      Eloranta J.J. , Hurst H.C.
      J. Biol. Chem.277:30798-30804(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TFAP2A; TFAP2B AND TFAP2C
    22. 22.
      "Role of two residues proximal to the active site of Ubc9 in substrate recognition by the Ubc9.SUMO-1 thiolester complex."
      Tatham M.H. , Chen Y. , Hay R.T.
      Biochemistry42:3168-3179(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF 100-ASP-LYS-101
    23. 23.
      "Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation."
      Tatham M.H. , Kim S. , Yu B. , Jaffray E. , Song J. , Zheng J. , Rodriguez M.S. , Hay R.T. , Chen Y.
      Biochemistry42:9959-9969(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SUMO1; SUMO2; SUMO3 AND THE UBLE1A-UBLE1B E1 COMPLEX;MUTAGENESIS OF 13-ARG-LYS-14 AND 17-ARG-LYS-18
    24. 24.
      "The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type."
      Pichler A. , Knipscheer P. , Saitoh H. , Sixma T.K. , Melchior F.
      Nat. Struct. Mol. Biol.11:984-991(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RANBP2
    25. 25.
      "Requirement of the coiled-coil domain of PML-RARalpha oncoprotein for localization, sumoylation, and inhibition of monocyte differentiation."
      Kim Y.E. , Kim D.Y. , Lee J.M. , Kim S.T. , Han T.H. , Ahn J.H.
      Biochem. Biophys. Res. Commun.330:746-754(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH THE PML-RARALPHA ONCOPROTEIN;FUNCTION
    26. 26.
      "Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection."
      Tatham M.H. , Kim S. , Jaffray E. , Song J. , Chen Y. , Hay R.T.
      Nat. Struct. Mol. Biol.12:67-74(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RANBP2;MUTAGENESIS OF PHE-22; VAL-25; VAL-27; GLU-42; LYS-48; GLU-54; LEU-57; LYS-59 AND ARG-61
    27. 27.
      "A general approach for investigating enzymatic pathways and substrates for ubiquitin-like modifiers."
      Li T. , Santockyte R. , Shen R.-F. , Tekle E. , Wang G. , Yang D.C.H. , Chock P.B.
      Arch. Biochem. Biophys.453:70-74(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY
    28. 28.
      "Ubc9 interacts with SOX4 and represses its transcriptional activity."
      Pan X. , Li H. , Zhang P. , Jin B. , Man J. , Tian L. , Su G. , Zhao J. , Li W. , Liu H. , Gong W. , Zhou T. , Zhang X.
      Biochem. Biophys. Res. Commun.344:727-734(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH SOX4
    29. 29.
      "Functional interaction between human herpesvirus 6 immediate-early 2 protein and ubiquitin-conjugating enzyme 9 in the absence of sumoylation."
      Tomoiu A. , Gravel A. , Tanguay R.M. , Flamand L.
      J. Virol.80:10218-10228(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HERPESVIRUS 6 IE2
    30. 30.
      "RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia."
      Carbia-Nagashima A. , Gerez J. , Perez-Castro C. , Paez-Pereda M. , Silberstein S. , Stalla G.K. , Holsboer F. , Arzt E.
      Cell131:309-323(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RWDD3;SUBCELLULAR LOCATION
    31. 31.
      "Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response."
      Cheng Z. , Ke Y. , Ding X. , Wang F. , Wang H. , Wang W. , Ahmed K. , Liu Z. , Xu Y. , Aikhionbare F. , Yan H. , Liu J. , Xue Y. , Yu J. , Powell M. , Liang S. , Wu Q. , Reddy S.E. , more...
      Oncogene27:931-941(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION OF KAT5-UBE2I-SENP6 COMPLEX
    32. 32.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    33. 33.
      "SUMOylation enhances DNA methyltransferase 1 activity."
      Lee B. , Muller M.T.
      Biochem. J.421:449-461(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DNMT1
    34. 34.
      "Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the steroidogenic acute regulatory gene."
      Kuo F.T. , Bentsi-Barnes I.K. , Barlow G.M. , Bae J. , Pisarska M.D.
      Cell. Signal.21:1935-1944(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FOXL2;ROLE IN FOXL2 SUMOYLATION;SUBCELLULAR LOCATION
    35. 35.
      "SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle."
      Figueroa-Romero C. , Iniguez-Lluhi J.A. , Stadler J. , Chang C.R. , Arnoult D. , Keller P.J. , Hong Y. , Blackstone C. , Feldman E.L.
      FASEB J.23:3917-3927(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DNM1L;FUNCTION IN DNM1L SUMOYLATION
    36. 36.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-65;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    37. 37.
      "Identification of a molecular recognition feature in the E1A oncoprotein that binds the SUMO conjugase UBC9 and likely interferes with polySUMOylation."
      Yousef A.F. , Fonseca G.J. , Pelka P. , Ablack J.N. , Walsh C. , Dick F.A. , Bazett-Jones D.P. , Shaw G.S. , Mymryk J.S.
      Oncogene29:4693-4704(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HUMAN ADENOVIRUS EARLY E1A PROTEIN
    38. 38.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    39. 39.
      "SUMOylation and SUMO-interacting motif (SIM) of metastasis tumor antigen 1 (MTA1) synergistically regulate its transcriptional repressor function."
      Cong L. , Pakala S.B. , Ohshiro K. , Li D.Q. , Kumar R.
      J. Biol. Chem.286:43793-43808(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MTA1
    40. 40.
      "The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G(1) arrest."
      Bennett R.L. , Pan Y. , Christian J. , Hui T. , May W.S. Jr.
      Cell Cycle11:407-417(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    41. 41.
      "Phosphorylation of Ubc9 by Cdk1 enhances SUMOylation activity."
      Su Y.F. , Yang T. , Huang H. , Liu L.F. , Hwang J.
      PLoS ONE7:E34250-E34250(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-71
    42. 42.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    43. 43.
      "UHRF2, a ubiquitin E3 ligase, acts as a small ubiquitin-like modifier E3 ligase for zinc finger protein 131."
      Oh Y. , Chung K.C.
      J. Biol. Chem.288:9102-9111(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UHRF2
    44. 44.
      "RSUME enhances glucocorticoid receptor SUMOylation and transcriptional activity."
      Druker J. , Liberman A.C. , Antunica-Noguerol M. , Gerez J. , Paez-Pereda M. , Rein T. , Iniguez-Lluhi J.A. , Holsboer F. , Arzt E.
      Mol. Cell. Biol.33:2116-2127(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NR3C1
    45. 45.
      "In silico structural and functional characterization of the RSUME splice variants."
      Gerez J. , Fuertes M. , Tedesco L. , Silberstein S. , Sevlever G. , Paez-Pereda M. , Holsboer F. , Turjanski A.G. , Arzt E.
      PLoS ONE8:E57795-E57795(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RWDD3
    46. 46.
      "Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system."
      Tong H. , Hateboer G. , Perrakis A. , Bernards R. , Sixma T.K.
      J. Biol. Chem.272:21381-21387(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS)
    47. 47.
      "Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1."
      Bernier-Villamor V. , Sampson D.A. , Matunis M.J. , Lima C.D.
      Cell108:345-356(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) IN COMPLEX WITH RANGAP1
    48. 48.
      "Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex."
      Reverter D. , Lima C.D.
      Nature435:687-692(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.01 ANGSTROMS) IN COMPLEX WITH SUMO1; RANGAP1 AND RANBP2
    49. 49.
      "Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway."
      Yunus A.A. , Lima C.D.
      Nat. Struct. Mol. Biol.13:491-499(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) IN COMPLEX WITH RANGAP1;MUTAGENESIS OF ASN-85; TYR-87 AND ASP-127
    50. 50.
      "Structure and analysis of a complex between SUMO and Ubc9 illustrates features of a conserved E2-Ubl interaction."
      Capili A.D. , Lima C.D.
      J. Mol. Biol.369:608-618(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) IN COMPLEX WITH SUMO1;INTERACTION WITH SUMO1; SUMO2 AND SUMO3;FUNCTION
    51. 51.
      "Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45."
      Sekiyama N. , Arita K. , Ikeda Y. , Hashiguchi K. , Ariyoshi M. , Tochio H. , Saitoh H. , Shirakawa M.
      Proteins78:1491-1502(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) IN COMPLEX WITH NFATC2IP/NIP45;INTERACTION WITH NFATC2IP;FUNCTION
    52. 52.
      "Structure of Importin13-Ubc9 complex: nuclear import and release of a key regulator of sumoylation."
      Grunwald M. , Bono F.
      EMBO J.30:427-438(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) IN COMPLEX WITH IPO13
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