USP10 ELISA Kit for Bovine(Bos taurus) | EIAab.comUSP10 ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > USP10(Gene name) > Bovine

USP10 (Gene name),

Ubiquitin carboxyl-terminal hydrolase 10 (Protein name ), UBP10_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

USP10;

Protein name:

Ubiquitin carboxyl-terminal hydrolase 10;

Alternative:

Ubiquitin thiolesterase 10;Deubiquitinating enzyme 10;Ubiquitin-specific-processing protease 10;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Interacts with G3BP, which may regulate its function. Interacts with p53/TP53, SNX3 and CFTR.

Function:

Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Does not deubiquitinate MDM2. Deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling.

Subcellular Location:

Cytoplasm Nucleus Early endosome Cytoplasmic in normal conditions. After DNA damage, translocates to the nucleus following phosphorylation by ATM.

Protein Attributes:

Sequence length:

800

Sequence:

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3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

bta:510164

UniGene:

Bt.27346

String:

A5PJS6

STRING:

9913.ENSBTAP00000012432

Pfam:

PF07145

Uniprot:

A5PJS6

FOR

ELISA Kit for Bovine Ubiquitin carboxyl-terminal hydrolase 10

CLIA Kit for Bovine Ubiquitin carboxyl-terminal hydrolase 10

Polyclonal Antibody for Bovine Ubiquitin carboxyl-terminal hydrolase 10

Monoclonal Antibody for Bovine Ubiquitin carboxyl-terminal hydrolase 10

Protein for Bovine Ubiquitin carboxyl-terminal hydrolase 10

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2007-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Fetal skin.

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