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Index > Protein center > USP14(Gene name) > Rabbit
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  • USP14 (Gene name),
  • Ubiquitin carboxyl-terminal hydrolase 14 (Protein name ),  UBP14_RABIT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    USP14(TGT);
    Protein name:
    Ubiquitin carboxyl-terminal hydrolase 14;
    Alternative:
    Ubiquitin thiolesterase 14;Deubiquitinating enzyme 14;Ubiquitin-specific-processing protease 14;
    Organism:
    Rabbit (Oryctolagus cuniculus). 
    General Annotation
    Sub Unit:
    Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1.
    Function:
    Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).
    Subcellular Location:
    Cytoplasm Cell membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    493
    Sequence:
    50:
    MPLYSVTVKW | GKEKFGGVEL | NTDEPPMVFK | AQLFALTGVQ | PARQRVMVKG | 
    100:
    GTLKDDDWGN | IKIKNGMTIL | MMGSADALPE | EPSAKTVFVE | DMTEEQLASA | 
    150:
    MELPCGLTNL | GNTCYMNATV | QCIRSVPELK | DALKRYAGAL | RASGEMASAQ | 
    200:
    YITAALRDLF | DSMDKTSSSI | PPIILLQFLH | MAFPQFAEKG | EQGQYLQQDA | 
    250:
    NECWIQMMRV | LQQKLEAIED | DSVKETDSSA | AAVAPSKKKS | LIDQFFGVEF | 
    300:
    ETTMKCTESE | EEEVTKGKEN | QLQLSCFINQ | EVKYLFTGLK | LRLQEEITKQ | 
    350:
    SPTLQRNALY | IKSSKISRLP | AYLTIQMVRF | FYKEKESVNA | KVLKDVKFPL | 
    400:
    MLDVYELCTP | ELQEKMVSFR | SKFKDIEDKK | VNQQPNASDK | KSSPQKEVRY | 
    450:
    EPFSFADDIG | SNNCGYYDLQ | AVLTHQGRSS | SSGHYVSWVK | RKHDEWIKFD | 
    493:
    DDKVSIVTPE | DILRLSGGGD | WHIAYVLLYG | PRRVEIMEEE | NEQ
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    SMR:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Cat.:
    E11578h
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    Packing:
    96T
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    ELISA Kit for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Cat.:
    E11578m
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    Packing:
    96T
    ELISA Kit for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Cat.:
    E11578b
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    Packing:
    96T
    ELISA Kit for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
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    CLIA Kit for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Cat.:
    U11578h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Cat.:
    U11578b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    MSDS:
    Please sign in first.
    CLIA Kit for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Cat.:
    U11578m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Cat.:
    P11578Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Polyclonal Antibody for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Polyclonal Antibody for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Cat.:
    P11578Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Monoclonal Antibody for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Monoclonal Antibody for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Monoclonal Antibody for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Protein for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Protein for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Protein for Rabbit Ubiquitin carboxyl-terminal hydrolase 14
    Protein for Rabbit Ubiquitin carboxyl-terminal hydrolase 14

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    References
    1. 1.
      "Cloning and characterization of cDNA encoding the rabbit tRNA-guanine transglycosylase 60-kilodalton subunit."
      Deshpande K.L. , Seubert P.H. , Tillman D.M. , Farkas W.R. , Katze J.R.
      Arch. Biochem. Biophys.326:1-7(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
      strain: New Zealand white.
      tissue: Liver.
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