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Index > Protein center > UGGT1(Gene name) > Human
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  • UGGT1 (Gene name),
  • UDP-glucose:glycoprotein glucosyltransferase 1 (Protein name ),  UGGG1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    UGGT1(GT;UGCGL1;UGGT;UGT1;UGTR);
    Protein name:
    UDP-glucose:glycoprotein glucosyltransferase 1(UGT1;hUGT1);
    Alternative:
    UDP-glucose ceramide glucosyltransferase-like 1;UDP--Glc:glycoprotein glucosyltransferase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer as well as in a tight complex with SEP15.
    Function:
    Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
    Subcellular Location:
    Endoplasmic reticulum lumen Endoplasmic reticulum-Golgi intermediate compartment
    Protein Attributes:
    Sequence length:
    1555
    Sequence:
    50:
    MGCKGDASGA | CAAGALPVTG | VCYKMGVLVV | LTVLWLFSSV | KADSKAITTS | 
    100:
    LTTKWFSTPL | LLEASEFLAE | DSQEKFWNFV | EASQNIGSSD | HDGTDYSYYH | 
    150:
    AILEAAFQFL | SPLQQNLFKF | CLSLRSYSAT | IQAFQQIAAD | EPPPEGCNSF | 
    200:
    FSVHGKKTCE | SDTLEALLLT | ASERPKPLLF | KGDHRYPSSN | PESPVVIFYS | 
    250:
    EIGSEEFSNF | HRQLISKSNA | GKINYVFRHY | IFNPRKEPVY | LSGYGVELAI | 
    300:
    KSTEYKAKDD | TQVKGTEVNT | TVIGENDPID | EVQGFLFGKL | RDLHPDLEGQ | 
    350:
    LKELRKHLVE | STNEMAPLKV | WQLQDLSFQT | AARILASPVE | LALVVMKDLS | 
    400:
    QNFPTKARAI | TKTAVSSELR | TEVEENQKYF | KGTLGLQPGD | SALFINGLHM | 
    450:
    DLDTQDIFSL | FDVLRNEARV | MEGLHRLGIE | GLSLHNVLKL | NIQPSEADYA | 
    500:
    VDIRSPAISW | VNNLEVDSRY | NSWPSSLQEL | LRPTFPGVIR | QIRKNLHNMV | 
    550:
    FIVDPAHETT | AELMNTAEMF | LSNHIPLRIG | FIFVVNDSED | VDGMQDAGVA | 
    600:
    VLRAYNYVAQ | EVDDYHAFQT | LTHIYNKVRT | GEKVKVEHVV | SVLEKKYPYV | 
    650:
    EVNSILGIDS | AYDRNRKEAR | GYYEQTGVGP | LPVVLFNGMP | FEREQLDPDE | 
    700:
    LETITMHKIL | ETTTFFQRAV | YLGELPHDQD | VVEYIMNQPN | VVPRINSRIL | 
    750:
    TAERDYLDLT | ASNNFFVDDY | ARFTILDSQG | KTAAVANSMN | YLTKKGMSSK | 
    800:
    EIYDDSFIRP | VTFWIVGDFD | SPSGRQLLYD | AIKHQKSSNN | VRISMINNPA | 
    850:
    KEISYENTQI | SRAIWAALQT | QTSNAAKNFI | TKMAKEGAAE | ALAAGADIAE | 
    900:
    FSVGGMDFSL | FKEVFESSKM | DFILSHAVYC | RDVLKLKKGQ | RAVISNGRII | 
    950:
    GPLEDSELFN | QDDFHLLENI | ILKTSGQKIK | SHIQQLRVEE | DVASDLVMKV | 
    1000:
    DALLSAQPKG | DPRIEYQFFE | DRHSAIKLRP | KEGETYFDVV | AVVDPVTREA | 
    1050:
    QRLAPLLLVL | AQLINMNLRV | FMNCQSKLSD | MPLKSFYRYV | LEPEISFTSD | 
    1100:
    NSFAKGPIAK | FLDMPQSPLF | TLNLNTPESW | MVESVRTPYD | LDNIYLEEVD | 
    1150:
    SVVAAEYELE | YLLLEGHCYD | ITTGQPPRGL | QFTLGTSANP | VIVDTIVMAN | 
    1200:
    LGYFQLKANP | GAWILRLRKG | RSEDIYRIYS | HDGTDSPPDA | DEVVIVLNNF | 
    1250:
    KSKIIKVKVQ | KKADMVNEDL | LSDGTSENES | GFWDSFKWGF | TGQKTEEVKQ | 
    1300:
    DKDDIINIFS | VASGHLYERF | LRIMMLSVLK | NTKTPVKFWF | LKNYLSPTFK | 
    1350:
    EFIPYMANEY | NFQYELVQYK | WPRWLHQQTE | KQRIIWGYKI | LFLDVLFPLV | 
    1400:
    VDKFLFVDAD | QIVRTDLKEL | RDFNLDGAPY | GYTPFCDSRR | EMDGYRFWKS | 
    1450:
    GYWASHLAGR | KYHISALYVV | DLKKFRKIAA | GDRLRGQYQG | LSQDPNSLSN | 
    1500:
    LDQDLPNNMI | HQVPIKSLPQ | EWLWCETWCD | DASKKRAKTI | DLCNNPMTKE | 
    1550:
    PKLEAAVRIV | PEWQDYDQEI | KQLQIRFQKE | KETGALYKEK | TKEPSREGPQ | 
    1555:
    KREEL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    KEGG:
    UniGene:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human UGT1
    ELISA Kit for Human UGT1
    ELISA Kit for Human UGT1
    CLIA Kit for Human UGT1
    CLIA Kit for Human UGT1
    CLIA Kit for Human UGT1
    Polyclonal Antibody for Human UGT1
    Polyclonal Antibody for Human UGT1
    Polyclonal Antibody for Human UGT1
    Monoclonal Antibody for Human UGT1
    Monoclonal Antibody for Human UGT1
    Monoclonal Antibody for Human UGT1
    Protein for Human UGT1
    Protein for Human UGT1
    Protein for Human UGT1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity."
      Arnold S.M. , Fessler L.I. , Fessler J.H. , Kaufman R.J.
      Biochemistry39:2149-2163(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;COFACTOR;INDUCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MUTAGENESIS OF ASP-1452; GLN-1453; ASP-1454; LEU-1455; PRO-1456 AND ASN-1457
      tissue: Fetal liver.
    2. 2.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Eye.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 710-1555 (ISOFORMS 1/2)
      tissue: Placenta.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    6. 6.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1277;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      "A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity."
      Cloutier P. , Lavallee-Adam M. , Faubert D. , Blanchette M. , Coulombe B.
      PLoS Genet.9:E1003210-E1003210(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH METTL23
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