Gene name:
UGGT1 (GT;UGCGL1;UGGT;UGT1;UGTR) ;
Protein name:
UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1;hUGT1) ;
Alternative:
UDP-glucose ceramide glucosyltransferase-like 1 ;UDP--Glc:glycoprotein glucosyltransferase ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Monomer as well as in a tight complex with SEP15.
Function:
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Subcellular Location:
Endoplasmic reticulum lumen
Endoplasmic reticulum-Golgi intermediate compartment
Protein Attributes:
50:
MGCKGDASGA | CAAGALPVTG | VCYKMGVLVV | LTVLWLFSSV | KADSKAITTS |
100:
LTTKWFSTPL | LLEASEFLAE | DSQEKFWNFV | EASQNIGSSD | HDGTDYSYYH |
150:
AILEAAFQFL | SPLQQNLFKF | CLSLRSYSAT | IQAFQQIAAD | EPPPEGCNSF |
200:
FSVHGKKTCE | SDTLEALLLT | ASERPKPLLF | KGDHRYPSSN | PESPVVIFYS |
250:
EIGSEEFSNF | HRQLISKSNA | GKINYVFRHY | IFNPRKEPVY | LSGYGVELAI |
300:
KSTEYKAKDD | TQVKGTEVNT | TVIGENDPID | EVQGFLFGKL | RDLHPDLEGQ |
350:
LKELRKHLVE | STNEMAPLKV | WQLQDLSFQT | AARILASPVE | LALVVMKDLS |
400:
QNFPTKARAI | TKTAVSSELR | TEVEENQKYF | KGTLGLQPGD | SALFINGLHM |
450:
DLDTQDIFSL | FDVLRNEARV | MEGLHRLGIE | GLSLHNVLKL | NIQPSEADYA |
500:
VDIRSPAISW | VNNLEVDSRY | NSWPSSLQEL | LRPTFPGVIR | QIRKNLHNMV |
550:
FIVDPAHETT | AELMNTAEMF | LSNHIPLRIG | FIFVVNDSED | VDGMQDAGVA |
600:
VLRAYNYVAQ | EVDDYHAFQT | LTHIYNKVRT | GEKVKVEHVV | SVLEKKYPYV |
650:
EVNSILGIDS | AYDRNRKEAR | GYYEQTGVGP | LPVVLFNGMP | FEREQLDPDE |
700:
LETITMHKIL | ETTTFFQRAV | YLGELPHDQD | VVEYIMNQPN | VVPRINSRIL |
750:
TAERDYLDLT | ASNNFFVDDY | ARFTILDSQG | KTAAVANSMN | YLTKKGMSSK |
800:
EIYDDSFIRP | VTFWIVGDFD | SPSGRQLLYD | AIKHQKSSNN | VRISMINNPA |
850:
KEISYENTQI | SRAIWAALQT | QTSNAAKNFI | TKMAKEGAAE | ALAAGADIAE |
900:
FSVGGMDFSL | FKEVFESSKM | DFILSHAVYC | RDVLKLKKGQ | RAVISNGRII |
950:
GPLEDSELFN | QDDFHLLENI | ILKTSGQKIK | SHIQQLRVEE | DVASDLVMKV |
1000:
DALLSAQPKG | DPRIEYQFFE | DRHSAIKLRP | KEGETYFDVV | AVVDPVTREA |
1050:
QRLAPLLLVL | AQLINMNLRV | FMNCQSKLSD | MPLKSFYRYV | LEPEISFTSD |
1100:
NSFAKGPIAK | FLDMPQSPLF | TLNLNTPESW | MVESVRTPYD | LDNIYLEEVD |
1150:
SVVAAEYELE | YLLLEGHCYD | ITTGQPPRGL | QFTLGTSANP | VIVDTIVMAN |
1200:
LGYFQLKANP | GAWILRLRKG | RSEDIYRIYS | HDGTDSPPDA | DEVVIVLNNF |
1250:
KSKIIKVKVQ | KKADMVNEDL | LSDGTSENES | GFWDSFKWGF | TGQKTEEVKQ |
1300:
DKDDIINIFS | VASGHLYERF | LRIMMLSVLK | NTKTPVKFWF | LKNYLSPTFK |
1350:
EFIPYMANEY | NFQYELVQYK | WPRWLHQQTE | KQRIIWGYKI | LFLDVLFPLV |
1400:
VDKFLFVDAD | QIVRTDLKEL | RDFNLDGAPY | GYTPFCDSRR | EMDGYRFWKS |
1450:
GYWASHLAGR | KYHISALYVV | DLKKFRKIAA | GDRLRGQYQG | LSQDPNSLSN |
1500:
LDQDLPNNMI | HQVPIKSLPQ | EWLWCETWCD | DASKKRAKTI | DLCNNPMTKE |
1550:
PKLEAAVRIV | PEWQDYDQEI | KQLQIRFQKE | KETGALYKEK | TKEPSREGPQ |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Polyclonal Antibody for Human UGT1
Polyclonal Antibody for Human UGT1
Polyclonal Antibody for Human UGT1
Monoclonal Antibody for Human UGT1
Monoclonal Antibody for Human UGT1
Monoclonal Antibody for Human UGT1
R&D Technical Data
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Precision
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Recovery
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Linearity
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;COFACTOR;INDUCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MUTAGENESIS OF ASP-1452; GLN-1453; ASP-1454; LEU-1455; PRO-1456 AND ASN-1457
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Eye .
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 710-1555 (ISOFORMS 1/2)
tissue :
Placenta .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1277;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH METTL23