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Index > Protein center > UPK1A(Gene name) > Human
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  • UPK1A (Gene name),
  • Uroplakin-1a (Protein name ),  UPK1A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    UPK1A(TSPAN21);
    Protein name:
    Uroplakin-1a(UP1a);
    Alternative:
    Uroplakin Ia(UPIa;UPKa);Tetraspanin-21(Tspan-21);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked. Interacts with uroplakin-2 (UPK2).
    Function:
    Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    258
    Sequence:
    50:
    MASAAAAEAE | KGSPVVVGLL | VVGNIIILLS | GLSLFAETIW | VTADQYRVYP | 
    100:
    LMGVSGKDDV | FAGAWIAIFC | GFSFFMVASF | GVGAALCRRR | SMVLTYLVLM | 
    150:
    LIVYIFECAS | CITSYTHRDY | MVSNPSLITK | QMLTFYSADT | DQGQELTRLW | 
    200:
    DRVMIEQECC | GTSGPMDWVN | FTSAFRAATP | EVVFPWPPLC | CRRTGNFIPL | 
    250:
    NEEGCRLGHM | DYLFTKGCFE | HIGHAIDSYT | WGISWFGFAI | LMWTLPVMLI | 
    258:
    AMYFYTML
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    Pfam:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human UP1a
    ELISA Kit for Human UP1a
    ELISA Kit for Human UP1a
    CLIA Kit for Human UP1a
    CLIA Kit for Human UP1a
    CLIA Kit for Human UP1a
    Polyclonal Antibody for Human UP1a
    Polyclonal Antibody for Human UP1a
    Polyclonal Antibody for Human UP1a
    Monoclonal Antibody for Human UP1a
    Monoclonal Antibody for Human UP1a
    Monoclonal Antibody for Human UP1a
    Protein for Human UP1a
    Protein for Human UP1a
    Protein for Human UP1a

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT THR-257
    3. 3.
      "Transcriptional control of the human urothelial-specific gene, uroplakin Ia."
      Hall G.D. , Weeks R.J. , Olsburgh J. , Southgate J. , Knowles M.A. , Selby P.J. , Chester J.D.
      Biochim. Biophys. Acta1729:126-134(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3-258 (ISOFORM 1);TISSUE SPECIFICITY
      tissue: Ureter.
    4. 4.
      "Uroplakin gene expression by normal and neoplastic human urothelium."
      Lobban E.D. , Smith B.A. , Hall G.D. , Harnden P. , Roberts P. , Selby P.J. , Trejdosiewicz L.K. , Southgate J.
      Am. J. Pathol.153:1957-1967(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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