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Index > Protein center > USP6NL(Gene name) > Human
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  • USP6NL (Gene name),
  • USP6 N-terminal-like protein (Protein name ),  US6NL_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    USP6NL(KIAA0019);
    Protein name:
    USP6 N-terminal-like protein;
    Alternative:
    Related to the N-terminus of tre(RN-tre);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with EPS8.
    Function:
    Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    828
    Sequence:
    50:
    MNSDQDVALK | LAQERAEIVA | KYDRGREGAE | IEPWEDADYL | VYKVTDRFGF | 
    100:
    LHEEELPDHN | VAVERQKHLE | IERTTKWLKM | LKGWEKYKNT | EKFHRRIYKG | 
    150:
    IPLQLRGEVW | ALLLEIPKMK | EETRDLYSKL | KHRARGCSPD | IRQIDLDVNR | 
    200:
    TFRDHIMFRD | RYGVKQQSLF | HVLAAYSIYN | TEVGYCQGMS | QITALLLMYM | 
    250:
    NEEDAFWALV | KLFSGPKHAM | HGFFVQGFPK | LLRFQEHHEK | ILNKFLSKLK | 
    300:
    QHLDSQEIYT | SFYTMKWFFQ | CFLDRTPFTL | NLRIWDIYIF | EGERVLTAMS | 
    350:
    YTILKLHKKH | LMKLSMEELV | EFFQETLAKD | FFFEDDFVIE | QLQISMTELK | 
    400:
    RAKLDLPEPG | KEDEYPKKPL | GQLPPELQSW | GVHHLSNGQR | SVGRPSPLAS | 
    450:
    GRRESGAPHR | RHEHSPHPQS | RTGTPERAQP | PRRKSVEEES | KKLKDEADFQ | 
    500:
    RKLPSGPQDS | SRQYNHAAAN | QNSNATSNIR | KEFVPKWNKP | SDVSATERTA | 
    550:
    KYTMEGKGRA | AHPALAVTVP | GPAEVRVSNV | RPKMKALDAE | DGKRGSTASQ | 
    600:
    YDNVPGPELD | SGASVEEALE | RAYSQSPRHA | LYPPSPRKHA | EPSSSPSKVS | 
    650:
    NKFTFKVQPP | SHARYPSQLD | GEARGLAHPP | SYSNPPVYHG | NSPKHFPTAN | 
    700:
    SSFASPQFSP | GTQLNPSRRP | HGSTLSVSAS | PEKSYSRPSP | LVLPSSRIEV | 
    750:
    LPVDTGAGGY | SGNSGSPKNG | KLIIPPVDYL | PDNRTWSEVS | YTYRPETQGQ | 
    800:
    SWTRDASRGN | LPKYSAFQLA | PFQDHGLPAV | SVDSPVRYKA | SPAAEDASPS | 
    828:
    GYPYSGPPPP | AYHYRNRDGL | SIQESVLL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    Pfam:
    MIM:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human USP6 N-terminal-like protein
    ELISA Kit for Human USP6 N-terminal-like protein
    CLIA Kit for Human USP6 N-terminal-like protein
    CLIA Kit for Human USP6 N-terminal-like protein
    Polyclonal Antibody for Human USP6 N-terminal-like protein
    Polyclonal Antibody for Human USP6 N-terminal-like protein
    Monoclonal Antibody for Human USP6 N-terminal-like protein
    Monoclonal Antibody for Human USP6 N-terminal-like protein
    Protein for Human USP6 N-terminal-like protein
    Protein for Human USP6 N-terminal-like protein

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "RN-tre identifies a family of tre-related proteins displaying a novel potential protein binding domain."
      Wong W.T. , Seki N. , Nagase T. , Nomura N. , Robbins K.C. , Di Fiore P.P. , Matoskova B.
      Oncogene12:2563-2571(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;INTERACTION WITH EPS8
    2. 2.
      "Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity."
      Ishibashi K. , Kanno E. , Itoh T. , Fukuda M.
      Genes Cells14:41-52(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Brain.
    3. 3.
      "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1."
      Nomura N. , Miyajima N. , Sazuka T. , Tanaka A. , Kawarabayasi Y. , Sato S. , Nagase T. , Seki N. , Ishikawa K. , Tabata S.
      DNA Res.1:27-35(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Bone marrow.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Trachea.
    5. 5.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Testis.
    8. 8.
      "Normalization and subtraction: two approaches to facilitate gene discovery."
      Bonaldo M.F. , Lennon G. , Soares M.B.
      Genome Res.6:791-806(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-202 (ISOFORM 2)
    9. 9.
      "The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5."
      Lanzetti L. , Rybin V. , Malabarba M.G. , Christoforidis S. , Scita G. , Zerial M. , Di Fiore P.P.
      Nature408:374-377(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF ARG-106; ASP-147 AND ARG-150
    10. 10.
      "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."
      Brill L.M. , Salomon A.R. , Ficarro S.B. , Mukherji M. , Stettler-Gill M. , Peters E.C.
      Anal. Chem.76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-582; SER-585 AND TYR-729;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    11. 11.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      "Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways."
      Fuchs E. , Haas A.K. , Spooner R.A. , Yoshimura S. , Lord J.M. , Barr F.A.
      J. Cell Biol.177:1133-1143(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF ARG-150
    13. 13.
      "Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells."
      Haas A.K. , Yoshimura S. , Stephens D.J. , Preisinger C. , Fuchs E. , Barr F.A.
      J. Cell Sci.120:2997-3010(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-391; SER-396 AND SER-716;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    15. 15.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    16. 16.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-716;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    17. 17.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-642; SER-655; SER-659; SER-680 AND SER-716;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    18. 18.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-716;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    19. 19.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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