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Index > Protein center > SLC14A2(Gene name) > Human
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  • SLC14A2 (Gene name),
  • Urea transporter 2 (Protein name ),  UT2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SLC14A2(HUT2;UT2);
    Protein name:
    Urea transporter 2;
    Alternative:
    Urea transporter, kidney;Solute carrier family 14 member 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Isoform 1 interacts with SNAPIN which may be important for recruitment to the plasma membrane.
    Function:
    Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.
    Subcellular Location:
    Apical cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    920
    Sequence:
    50:
    MSDPHSSPLL | PEPLSSRYKL | YEAEFTSPSW | PSTSPDTHPA | LPLLEMPEEK | 
    100:
    DLRSSNEDSH | IVKIEKLNER | SKRKDDGVAH | RDSAGQRCIC | LSKAVGYLTG | 
    150:
    DMKEYRIWLK | DKHLALQFID | WVLRGTAQVM | FINNPLSGLI | IFIGLLIQNP | 
    200:
    WWTITGGLGT | VVSTLTALAL | GQDRSAIASG | LHGYNGMLVG | LLMAVFSEKL | 
    250:
    DYYWWLLFPV | TFTAMSCPVL | SSALNSIFSK | WDLPVFTLPF | NIAVTLYLAA | 
    300:
    TGHYNLFFPT | TLVEPVSSVP | NITWTEMEMP | LLLQAIPVGV | GQVYGCDNPW | 
    350:
    TGGVFLVALF | ISSPLICLHA | AIGSIVGLLA | ALSVATPFET | IYTGLWSYNC | 
    400:
    VLSCIAIGGM | FYALTWQTHL | LALICALFCA | YMEAAISNIM | SVVGVPPGTW | 
    450:
    AFCLATIIFL | LLTTNNPAIF | RLPLSKVTYP | EANRIYYLTV | KSGEEEKAPS | 
    500:
    GGGGEHPPTA | GPKVEEGSEA | VLSKHRSVFH | IEWSSIRRRS | KVFGKGEHQE | 
    550:
    RQNKDPFPYR | YRKPTVELLD | LDTMEESSEI | KVETNISKTS | WIRSSMAASG | 
    600:
    KRVSKALSYI | TGEMKECGEG | LKDKSPVFQF | FDWVLRGTSQ | VMFVNNPLSG | 
    650:
    ILIILGLFIQ | NPWWAISGCL | GTIMSTLTAL | ILSQDKSAIA | AGFHGYNGVL | 
    700:
    VGLLMAVFSD | KGDYYWWLLL | PVIIMSMSCP | ILSSALGTIF | SKWDLPVFTL | 
    750:
    PFNITVTLYL | AATGHYNLFF | PTTLLQPASA | MPNITWSEVQ | VPLLLRAIPV | 
    800:
    GIGQVYGCDN | PWTGGIFLIA | LFISSPLICL | HAAIGSTMGM | LAALTIATPF | 
    850:
    DSIYFGLCGF | NSTLACIAIG | GMFYVITWQT | HLLAIACALF | AAYLGAALAN | 
    900:
    MLSVFGLPPC | TWPFCLSALT | FLLLTTNNPA | IYKLPLSKVT | YPEANRIYYL | 
    920:
    SQERNRRASI | ITKYQAYDVS | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    KEGG:
    UniGene:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Urea transporter 2
    ELISA Kit for Human Urea transporter 2
    ELISA Kit for Human Urea transporter 2
    ELISA Kit for Human Urea transporter 2
    CLIA Kit for Human Urea transporter 2
    CLIA Kit for Human Urea transporter 2
    CLIA Kit for Human Urea transporter 2
    CLIA Kit for Human Urea transporter 2
    Polyclonal Antibody for Human Urea transporter 2
    Polyclonal Antibody for Human Urea transporter 2
    Polyclonal Antibody for Human Urea transporter 2
    Polyclonal Antibody for Human Urea transporter 2
    Monoclonal Antibody for Human Urea transporter 2
    Monoclonal Antibody for Human Urea transporter 2
    Monoclonal Antibody for Human Urea transporter 2
    Monoclonal Antibody for Human Urea transporter 2
    Protein for Human Urea transporter 2
    Protein for Human Urea transporter 2
    Protein for Human Urea transporter 2
    Protein for Human Urea transporter 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular characterization of a new urea transporter in the human kidney."
      Olives B. , Sonia M. , Mattei M.-G. , Matassi G. , Rousselet G. , Ripoche P. , Cartron J.-P. , Bailly P.
      FEBS Lett.386:156-160(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;TISSUE SPECIFICITY
      tissue: Kidney.
    2. 2.
      "Cloning and characterization of the human urea transporter UT-A1 and mapping of the human Slc14a2 gene."
      Bagnasco S.M. , Peng T. , Janech M.G. , Karakashian A. , Sands J.M.
      Am. J. Physiol.281:F400-F406(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;VARIANTS VAL-132 AND GLN-510
      tissue: Kidney.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS VAL-132 AND GLN-510
      tissue: Testis.
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS VAL-132; GLN-510 AND THR-880
    5. 6.
      "The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein."
      Mistry A.C. , Mallick R. , Froehlich O. , Klein J.D. , Rehm A. , Chen G. , Sands J.M.
      J. Biol. Chem.282:30097-30106(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SNAPIN
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