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Index > Protein center > Ppip5k1(Gene name) > Rat
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  • Ppip5k1 (Gene name),
  • Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 (Protein name ),  VIP1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Ppip5k1(Hisppd2a;Vip1);
    Protein name:
    Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1;
    Alternative:
    Histidine acid phosphatase domain-containing protein 2A;Diphosphoinositol pentakisphosphate kinase 1;VIP1 homolog;InsP6 and PP-IP5 kinase 1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Bifunctional inositol kinase that catalyzes the formation of diphosphoinositol pentakisphosphate (InsP7 or PP-InsP5) and bi-diphosphoinositol tetrakisphosphate (InsP8 or PP2-InsP4). Converts inositolitol hexakisphosphate (InsP6) to InsP7. Also able to convert InsP7 to InsP8. Probably specifically mediates the formation of 4PP-InsP5 and 6PP-InsP5 InsP7 isomers but not of 5PP-IP5 InsP7 isomer. Activated when cells are exposed to hyperosmotic stress.
    Subcellular Location:
    Cytoplasm cytosol
    Protein Attributes:
    Sequence length:
    1434
    Sequence:
    50:
    MWSLTANEDE | DESATAHFFL | GAGDEGLGTC | GIGMRTGESD | SELLEDEEDE | 
    100:
    VPPEPQIIVG | ICAMTKKSKS | KPMTQILERL | CRFDYLTVVI | LGEDVILNEP | 
    150:
    VENWPPCHCL | ISFHSKGFPL | DKAVAYSKLR | NPFLINDLTM | QYYIQDRREV | 
    200:
    YRILQEEGID | LPRYAVLNRD | PACPEECNLI | EGEDQVEVNG | AVFPKPFVEK | 
    250:
    PVSAEDHNVY | IYYPSSAGGG | SQRLFRKIGS | RSSVYSPESS | VRKTGSYIYE | 
    300:
    EFMPTDGTDV | KVYTVGPDYA | HAEARKSPAL | DGKVERDSEG | KEVRYPVMLT | 
    350:
    AMEKLVARKV | CVAFKQTVCG | FDLLRANGHS | FVCDVNGFSF | VKNSMKYYDD | 
    400:
    CAKILGNTIM | RELAPQFQIP | WSIPTEAEDI | PIVPTTSGTM | MELRCVIAII | 
    450:
    RHGDRTPKQK | MKMEVTHPRF | FALFEKHGGY | KTGKLKLKRP | EQLQEVLDIT | 
    500:
    RLLLAELEKE | PGAEIEEKTG | KLEQLKSVLE | MYGHFSGINR | KVQLTYYPHG | 
    550:
    VKASSEGQDL | QREPPAPSLL | LVLKWGGELT | PDGRVQAEEL | GRAFRCMYPG | 
    600:
    GQGDYAGFPG | CGLLRLHSTF | RHDLKIYASD | EGRVQMTAAA | FAKGLLALEG | 
    650:
    ELTPILVQMV | KSANMNGLLD | SDSDSLSSCQ | HRVKARLHHI | LQQDAPFGPE | 
    700:
    DYDQLAPTGS | TSLLNSMSVI | QNPVKVCDQV | FALIENLTHQ | IRERMQDPSS | 
    750:
    VDLQLYHSET | LELMLQRWSK | LERDFRQKSG | RYDISKIPDI | YDCVKYDVQH | 
    800:
    NGSLGLQGTA | ELLRLSKALA | DVVIPQEYGI | SREEKVEIAV | GFCLPLLRKI | 
    850:
    LLDLQRTHED | ESVNKLHPLY | SRGVLSPGRH | VRTRLYFTSE | SHVHSLLSVF | 
    900:
    RYGGLLDETK | DAQWQRALAY | LSAISELNYM | TQIVIMLYED | NTRDPLSEER | 
    950:
    FHVELHFSPG | VKGVEEGSAP | AGCGFRPASS | ENEEMKTDPG | SIENLCPAKP | 
    1000:
    SDEPDRALQT | SPQPVEGTGL | PRRSPLIRNR | KAGSMEVLSE | TSSSRPGGYR | 
    1050:
    LFSSSRPPTE | MKQSGLGSQC | TGLFSTTVLG | GSSSAPNLQD | YARTHGKKLP | 
    1100:
    PAGLKHRDEL | LFVPAVKRFS | VSFAKHPTNG | FEGCSMVPTI | YPLETLHNAL | 
    1150:
    SLRQVSEFLT | KVCQRHTDAH | AQASAALFDS | MHNHQASDNP | FSPPRTLHSP | 
    1200:
    PLQLRHRSEK | PPWYSSGPSS | TVSSAGPSSP | TTVDGNSHFG | FSDQSSVNTQ | 
    1250:
    MIEEKQGLGL | LQETPGDGTP | EFHIELAEST | QSPQEPPVEI | SPPGSQDDTE | 
    1300:
    VNQTCQEVPD | TIQPCHDILE | EIGQPNQEVP | DISQLLLKNH | DTATNTCQPC | 
    1350:
    QASQLSKKVY | EEICQLCQDN | PEESNQLCQE | VSVELGRMVH | RFPVSIGSTT | 
    1400:
    QETLMEIGRP | TQEIPEEPCQ | EFSEKVGMLT | QKASAISELS | QDILETDNPS | 
    1434:
    QELSEETDLQ | AQEVSEEIDQ | EPEVVDELSN | EDIS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    ELISA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    ELISA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    ELISA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    CLIA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    CLIA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    CLIA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    CLIA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Polyclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Polyclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Polyclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Polyclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Monoclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Monoclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Monoclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Monoclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Protein for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Protein for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Protein for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Protein for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress."
      Choi J.H. , Williams J. , Cho J. , Falck J.R. , Shears S.B.
      J. Biol. Chem.282:30763-30775(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;FUNCTION;CATALYTIC ACTIVITY
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