Gene name:
Ppip5k1 (Hisppd2a;Vip1) ;
Protein name:
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 ;
Alternative:
Histidine acid phosphatase domain-containing protein 2A ;Diphosphoinositol pentakisphosphate kinase 1 ;VIP1 homolog ;InsP6 and PP-IP5 kinase 1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Bifunctional inositol kinase that catalyzes the formation of diphosphoinositol pentakisphosphate (InsP7 or PP-InsP5) and bi-diphosphoinositol tetrakisphosphate (InsP8 or PP2-InsP4). Converts inositolitol hexakisphosphate (InsP6) to InsP7. Also able to convert InsP7 to InsP8. Probably specifically mediates the formation of 4PP-InsP5 and 6PP-InsP5 InsP7 isomers but not of 5PP-IP5 InsP7 isomer. Activated when cells are exposed to hyperosmotic stress.
Subcellular Location:
Cytoplasm
cytosol
Protein Attributes:
50:
MWSLTANEDE | DESATAHFFL | GAGDEGLGTC | GIGMRTGESD | SELLEDEEDE |
100:
VPPEPQIIVG | ICAMTKKSKS | KPMTQILERL | CRFDYLTVVI | LGEDVILNEP |
150:
VENWPPCHCL | ISFHSKGFPL | DKAVAYSKLR | NPFLINDLTM | QYYIQDRREV |
200:
YRILQEEGID | LPRYAVLNRD | PACPEECNLI | EGEDQVEVNG | AVFPKPFVEK |
250:
PVSAEDHNVY | IYYPSSAGGG | SQRLFRKIGS | RSSVYSPESS | VRKTGSYIYE |
300:
EFMPTDGTDV | KVYTVGPDYA | HAEARKSPAL | DGKVERDSEG | KEVRYPVMLT |
350:
AMEKLVARKV | CVAFKQTVCG | FDLLRANGHS | FVCDVNGFSF | VKNSMKYYDD |
400:
CAKILGNTIM | RELAPQFQIP | WSIPTEAEDI | PIVPTTSGTM | MELRCVIAII |
450:
RHGDRTPKQK | MKMEVTHPRF | FALFEKHGGY | KTGKLKLKRP | EQLQEVLDIT |
500:
RLLLAELEKE | PGAEIEEKTG | KLEQLKSVLE | MYGHFSGINR | KVQLTYYPHG |
550:
VKASSEGQDL | QREPPAPSLL | LVLKWGGELT | PDGRVQAEEL | GRAFRCMYPG |
600:
GQGDYAGFPG | CGLLRLHSTF | RHDLKIYASD | EGRVQMTAAA | FAKGLLALEG |
650:
ELTPILVQMV | KSANMNGLLD | SDSDSLSSCQ | HRVKARLHHI | LQQDAPFGPE |
700:
DYDQLAPTGS | TSLLNSMSVI | QNPVKVCDQV | FALIENLTHQ | IRERMQDPSS |
750:
VDLQLYHSET | LELMLQRWSK | LERDFRQKSG | RYDISKIPDI | YDCVKYDVQH |
800:
NGSLGLQGTA | ELLRLSKALA | DVVIPQEYGI | SREEKVEIAV | GFCLPLLRKI |
850:
LLDLQRTHED | ESVNKLHPLY | SRGVLSPGRH | VRTRLYFTSE | SHVHSLLSVF |
900:
RYGGLLDETK | DAQWQRALAY | LSAISELNYM | TQIVIMLYED | NTRDPLSEER |
950:
FHVELHFSPG | VKGVEEGSAP | AGCGFRPASS | ENEEMKTDPG | SIENLCPAKP |
1000:
SDEPDRALQT | SPQPVEGTGL | PRRSPLIRNR | KAGSMEVLSE | TSSSRPGGYR |
1050:
LFSSSRPPTE | MKQSGLGSQC | TGLFSTTVLG | GSSSAPNLQD | YARTHGKKLP |
1100:
PAGLKHRDEL | LFVPAVKRFS | VSFAKHPTNG | FEGCSMVPTI | YPLETLHNAL |
1150:
SLRQVSEFLT | KVCQRHTDAH | AQASAALFDS | MHNHQASDNP | FSPPRTLHSP |
1200:
PLQLRHRSEK | PPWYSSGPSS | TVSSAGPSSP | TTVDGNSHFG | FSDQSSVNTQ |
1250:
MIEEKQGLGL | LQETPGDGTP | EFHIELAEST | QSPQEPPVEI | SPPGSQDDTE |
1300:
VNQTCQEVPD | TIQPCHDILE | EIGQPNQEVP | DISQLLLKNH | DTATNTCQPC |
1350:
QASQLSKKVY | EEICQLCQDN | PEESNQLCQE | VSVELGRMVH | RFPVSIGSTT |
1400:
QETLMEIGRP | TQEIPEEPCQ | EFSEKVGMLT | QKASAISELS | QDILETDNPS |
1434:
QELSEETDLQ | AQEVSEEIDQ | EPEVVDELSN | EDIS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
Bovine
ELISA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
ELISA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
ELISA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
ELISA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
CLIA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
CLIA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
CLIA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
CLIA Kit for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Polyclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Polyclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Polyclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Polyclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Monoclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Monoclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Monoclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Monoclonal Antibody for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Protein for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Protein for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Protein for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Protein for Rat Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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more...
Nature428:493-521(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Brown Norway .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY;FUNCTION;CATALYTIC ACTIVITY