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Index > Protein center > VNN1(Gene name) > Human
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  • VNN1 (Gene name),
  • Pantetheinase (Protein name ),  VNN1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    VNN1;
    Protein name:
    Pantetheinase;
    Alternative:
    Tiff66;Pantetheine hydrolase;Vascular non-inflammatory molecule 1(Vanin-1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor
    Protein Attributes:
    Sequence length:
    513
    Sequence:
    50:
    MTTQLPAYVA | ILLFYVSRAS | CQDTFTAAVY | EHAAILPNAT | LTPVSREEAL | 
    100:
    ALMNRNLDIL | EGAITSAADQ | GAHIIVTPED | AIYGWNFNRD | SLYPYLEDIP | 
    150:
    DPEVNWIPCN | NRNRFGQTPV | QERLSCLAKN | NSIYVVANIG | DKKPCDTSDP | 
    200:
    QCPPDGRYQY | NTDVVFDSQG | KLVARYHKQN | LFMGENQFNV | PKEPEIVTFN | 
    250:
    TTFGSFGIFT | CFDILFHDPA | VTLVKDFHVD | TIVFPTAWMN | VLPHLSAVEF | 
    300:
    HSAWAMGMRV | NFLASNIHYP | SKKMTGSGIY | APNSSRAFHY | DMKTEEGKLL | 
    350:
    LSQLDSHPSH | SAVVNWTSYA | SSIEALSSGN | KEFKGTVFFD | EFTFVKLTGV | 
    400:
    AGNYTVCQKD | LCCHLSYKMS | ENIPNEVYAL | GAFDGLHTVE | GRYYLQICTL | 
    450:
    LKCKTTNLNT | CGDSAETAST | RFEMFSLSGT | FGTQYVFPEV | LLSENQLAPG | 
    500:
    EFQVSTDGRL | FSLKPTSGPV | LTVTLFGRLY | EKDWASNASS | GLTAQARIIM | 
    513:
    LIVIAPIVCS | LSW
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    MIM:
    UniGene:
    Pfam:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Pantetheinase
    Cat.:
    E1443h
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    ELISA Kit for Human Pantetheinase
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    E1443m
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    ELISA Kit for Human Pantetheinase
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    E1443d
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    96T
    ELISA Kit for Human Pantetheinase
    Cat.:
    E1443p
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    ELISA Kit for Human Pantetheinase
    Cat.:
    E1443b
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    Packing:
    96T
    CLIA Kit for Human Pantetheinase
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    U1443p
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    96T
    CLIA Kit for Human Pantetheinase
    Cat.:
    U1443d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Pantetheinase
    Cat.:
    U1443h
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Pantetheinase
    Cat.:
    U1443b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Pantetheinase
    Cat.:
    U1443m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Pantetheinase
    Polyclonal Antibody for Human Pantetheinase
    Polyclonal Antibody for Human Pantetheinase
    Cat.:
    P1443Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Pantetheinase
    Cat.:
    P1443Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Pantetheinase
    Monoclonal Antibody for Human Pantetheinase
    Monoclonal Antibody for Human Pantetheinase
    Monoclonal Antibody for Human Pantetheinase
    Monoclonal Antibody for Human Pantetheinase
    Monoclonal Antibody for Human Pantetheinase
    Protein for Human Pantetheinase
    Protein for Human Pantetheinase
    Protein for Human Pantetheinase
    Protein for Human Pantetheinase
    Protein for Human Pantetheinase

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    Linearity
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    References
    1. 1.
      "Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6."
      Galland F. , Malergue F. , Bazin H. , Mattei M.-G. , Aurrand-Lions M. , Theillet C. , Naquet P.
      Genomics53:203-213(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ILE-26
      tissue: Liver.
    2. 2.
      "Human Tiff66."
      Prehn S. , Friedrichson T. , Henske A. , Boehm S. , Hartmann E. , Kurzchalia T.V.
      Submitted (1995-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ILE-26
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ILE-26
      tissue: Umbilical cord blood.
    4. 4.
      NIEHS SNPs program
      Submitted (2005-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ILE-26; THR-63; SER-131; LEU-136; ASN-146; ASP-296; GLU-325; ALA-336 AND THR-373
    5. 5.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-131
    7. 7.
      "Is pantetheinase the actual identity of mouse and human vanin-1 proteins?"
      Maras B. , Barra D. , Dupre S. , Pitari G.
      FEBS Lett.461:149-152(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    8. 8.
      "Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes."
      Martin F. , Malergue F. , Pitari G. , Philippe J.M. , Philips S. , Chabret C. , Granjeaud S. , Mattei M.G. , Mungall A.J. , Naquet P. , Galland F.
      Immunogenetics53:296-306(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-38 AND ASN-353
      tissue: Bile.
    10. 10.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-130; ASN-283; ASN-315 AND ASN-353
      tissue: Plasma.
    11. 11.
      "Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines."
      Jansen P.A.M. , Kamsteeg M. , Rodijk-Olthuis D. , van Vlijmen-Willems I.M.J.J. , de Jongh G.J. , Bergers M. , Tjabringa G.S. , Zeeuwen P.L.J.M. , Schalkwijk J.
      J. Invest. Dermatol.129:2167-2174(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION BY CYTOKINES
    12. 12.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-353
      tissue: Liver.
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