Protein name:
Serine/threonine-protein kinase VRK1 ;
Alternative:
Vaccinia-related kinase 1 ;
Organism:
Bovine (Bos taurus).
General Annotation
Function:
Serine/threonine kinase that phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm.
Subcellular Location:
Cytoplasm
Nucleus
Cytoplasm
cytoskeleton
spindle
Dispersed throughout the cell but not located on mitotic spindle or chromatids during mitosis.
Protein Attributes:
50:
MPRVKAAQAG | RQGPAKRRLA | EHFAAGEIIT | DMNKKEWKLG | SPIGQGGFGC |
100:
IYLADMNSSK | SVGNDAPCVV | KVEPSDNGPL | FTELKFYQRA | AKPEQIQKWI |
150:
RTHKLKYLGV | PKYWGSGLHD | KNGKSYRFMI | IDRFGSDLQK | IYEANAKRFS |
200:
RKTVLQLSLR | ILDILEYIHE | HEYVHGDIKA | SNLLLSYKNP | DQVYLVDYGL |
250:
AYRYCPEGTH | KEYKEDPKRC | HDGTVEFTSI | DAHNGVAPSR | RGDLEILGYC |
300:
MIQWLSGHLP | WEDNLKDPNY | VRDSKIRYRE | NIASLMDKCF | PEKNKPDEIA |
350:
KYMETVKLLD | YVEKPLYQKL | RDILLQGLKA | IGSKDDGKLD | LTVVENGSLK |
396:
AKPVAKKRKK | EAEESVESSV | EDMECSDKQT | EEATQTRSKT | RKRVQK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
ELISA Kit for Bovine Serine/threonine-protein kinase VRK1
ELISA Kit for Bovine Serine/threonine-protein kinase VRK1
ELISA Kit for Bovine Serine/threonine-protein kinase VRK1
CLIA Kit for Bovine Serine/threonine-protein kinase VRK1
CLIA Kit for Bovine Serine/threonine-protein kinase VRK1
CLIA Kit for Bovine Serine/threonine-protein kinase VRK1
Polyclonal Antibody for Bovine Serine/threonine-protein kinase VRK1
Polyclonal Antibody for Bovine Serine/threonine-protein kinase VRK1
Polyclonal Antibody for Bovine Serine/threonine-protein kinase VRK1
Monoclonal Antibody for Bovine Serine/threonine-protein kinase VRK1
Monoclonal Antibody for Bovine Serine/threonine-protein kinase VRK1
Monoclonal Antibody for Bovine Serine/threonine-protein kinase VRK1
Protein for Bovine Serine/threonine-protein kinase VRK1
Protein for Bovine Serine/threonine-protein kinase VRK1
Protein for Bovine Serine/threonine-protein kinase VRK1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"A whole-genome assembly of the domestic cow, Bos taurus."
Zimin A.V.
,
Delcher A.L.
,
Florea L.
,
Kelley D.R.
,
Schatz M.C.
,
Puiu D.
,
Hanrahan F.
,
Pertea G.
,
Van Tassell C.P.
,
Sonstegard T.S.
,
Marcais G.
,
Roberts M.
,
Subramanian P.
,
Yorke J.A.
,
Salzberg S.L.
Genome Biol.10:R42.01-R42.10(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Hereford .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Crossbred X Angus .
tissue :
Ileum .