WASF1 ELISA Kit for Bovine(Bos taurus) | EIAab.comWASF1 ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > WASF1(Gene name) > Bovine

WASF1 (Gene name),

Wiskott-Aldrich syndrome protein family member 1 (Protein name ), WASF1_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

WASF1;

Protein name:

Wiskott-Aldrich syndrome protein family member 1(WASP family protein member 1);

Alternative:

Protein WAVE-1;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Component of the WAVE1 complex composed of ABI2, CYFIP1 or CYFIP2, BRK1, NCKAP1 and WASF1/WAVE1. Within the complex, a heterdimer containing NCKAP1 and CYFIP1 interacts with a heterotrimer formed by WAVE1, ABI2 and BRK1. CYFIP2 binds to activated RAC1 which causes the complex to dissociate, releasing activated WASF1. The complex can also be activated by NCK1. Binds actin and the Arp2/3 complex. Interacts with BAIAP2.

Function:

Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.

Subcellular Location:

Cytoplasm cytoskeleton Dot-like pattern in the cytoplasm. Concentrated in Rac-regulated membrane-ruffling areas.

Protein Attributes:

Sequence length:

559

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

559:

EFDEVDWLE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Bt.16190

Pfam:

PF02205

String:

Q0IIJ3

KEGG:

bta:531488

STRING:

9913.ENSBTAP00000022116

Uniprot:

Q0IIJ3

FOR

ELISA Kit for Bovine WASP family protein member 1

CLIA Kit for Bovine WASP family protein member 1

Polyclonal Antibody for Bovine WASP family protein member 1

Monoclonal Antibody for Bovine WASP family protein member 1

Protein for Bovine WASP family protein member 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2006-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Basal ganglia.
2.

"Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck."
Eden S. , Rohatgi R. , Podtelejnikov A.V. , Mann M. , Kirschner M.W.
Nature418:790-793(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COMPONENT OF WAVE1 COMPLEX

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