Wee1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comWee1 ELISA Kit for Rat(Rattus norvegicus)

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Wee1 (Gene name),

Wee1-like protein kinase (Protein name ), WEE1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Wee1;

Protein name:

Wee1-like protein kinase;

Alternative:

Wee1A kinase;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Binds to 14-3-3 protein zeta.

Function:

Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

646

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

646:

QMAAKVAAEE | RALLTDRMAT | RSTTQSNRTS | RLIGKKMNRS | VSLTIY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.208255

String:

Q63802

SMR:

Q63802

KEGG:

rno:308937

Pfam:

PF00069

Uniprot:

Q63802

FOR

ELISA Kit for Rat Wee1-like protein kinase

CLIA Kit for Rat Wee1-like protein kinase

Polyclonal Antibody for Rat Wee1-like protein kinase

Monoclonal Antibody for Rat Wee1-like protein kinase

Protein for Rat Wee1-like protein kinase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

Furunobu A.
Submitted (1994-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Ovary.

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