Gene name:
Wnk1 (Hsn2;Prkwnk1) ;
Protein name:
Serine/threonine-protein kinase WNK1 ;
Alternative:
Protein kinase with no lysine 1 ;Protein kinase lysine-deficient 1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with SYT2 (By similarity). Interacts with WNK3 and WNK4.
Function:
Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MSDGAAEKQS | GTPGFLTPPA | PVPKNGSSSD | SSVGEKLGAT | VADSGVGRTE |
100:
EYRRRRHTMD | KDSRGAAATT | TPTEHRFFRR | SVICDSNATA | LELPGLPLSI |
150:
PQPSVPAVVP | QSAPPEPHRE | ETLTATVASQ | VSQQPSAAAS | PGEQAVVGSA |
200:
TTTVPSSTSK | DRPVSQPSLV | GSKEEPPPSR | SGSGSGGASA | KEAQEDRSQQ |
250:
QDDIEELETK | AVGMSNDGRF | LKFDIEIGRG | SFKTVYKGLD | TETTVEVAWC |
300:
ELQDRKLTKS | ERQRFKEEAE | MLKGLQHPNI | VRFYDSWEST | VKGKKCIVLV |
350:
TELMTSGTLK | TYLKRFKVMK | IKVLRSWCRQ | ILKGLQFLHT | RTPPIIHRDL |
400:
KCDNIFITGP | TGSVKIGDLG | LATLKRASFA | KSVIGTPEFM | APEMYEEKYD |
450:
ESVDVYAFGM | CMLEMATSEY | PYSECQNAAQ | IYRRVTSGVK | PASFDKVAIP |
500:
EVKEIIEGCI | RQNKDERYSI | KDLLNHAFFQ | EETGVRVELA | EEDDGEKIAI |
550:
KLWLRIEDIK | KLKGKYKDNE | AIEFSFDLER | DVPEDVAQEM | VESGYVCEGD |
600:
HKTMAKAIKD | RVSLIKRKRE | QRQLVREEQE | KRKQEESSFK | QQNEQQASVS |
650:
QAGIQQLSAA | STGIPTAPAT | SASVSTQVEP | EEPEADQHQQ | LQYQQPSISV |
700:
LSDGTIDSGQ | GSSVFTESRV | SSQQTVSYGS | QHEQAHSTGT | APGHTVSSIQ |
750:
AQSQPHGVYP | PSSMAQGQNQ | GQPSSSLAGV | LSSQPIQHPQ | QQGIQPTVPS |
800:
QQAVQYSLPQ | AASSSEGTTA | QPVSQPQVSA | GTQLPVSQTV | ATVQGEPHIP |
850:
VSTQPSVVPV | HSGAHFLPMG | QPIPTSLLPQ | YPVSQIPIST | PHVSTAQTGF |
900:
SSVPITMAAG | INQPLLTLAS | SATASSIPGG | SPVVPNQLPT | LLQPVNQLQS |
950:
QVHPQLLQPT | TVQSIGIPAN | LGQAAEGPLP | SGDVLYQGFP | SRLPPQYPGD |
1000:
SNIAPSSNVA | SVCIHSTVLA | PPSMPTEALA | TQGYFPTVVQ | PYVESTPLVP |
1050:
MGSVGGQVQV | SQPAVSLTQQ | PPTTSSQQAV | LESTQGVSQA | APPEQTPITQ |
1100:
SQPTQPVPLV | TSADSAHSDV | ASGMSDGNEN | APSSSGRHEG | RTTKRHYRKS |
1150:
VRSRSRHEKT | SRPKLRILNV | SNKGDRVVEC | QLETHNRKMV | TFKFDLDGDN |
1200:
PEEIATIMVN | NDFILAIERE | SFVAQVREII | EKADEMLSED | VSVEPEGDQG |
1250:
LESLQGKDDY | GFPGSQKLEG | EFKQPIAVSS | MPQQIGVPTS | SLTQVVHSAG |
1300:
RRFIVSPVPE | SRLRESKVFT | SDISDPVVAS | TSQAPGMNLS | HSASSLSLQQ |
1350:
AFSELKHGQM | TEGPNTAPPN | FNHMAGPTFS | PFLASIAGVQ | TVAASTPSVS |
1400:
VPITSSPLND | ISTSVMQSET | ALPTEKGIVG | VTTTSTGVVA | SGGLTTMSVS |
1450:
ESPTSSSAVS | SSTVPAVVTV | STPSQPVQAS | TSGSIASSTG | SFPPGTFSTT |
1500:
TATTMGSVVA | PDAKPPTVLL | QQVASNTAGV | AIVTSVSTTT | PFPGMASQPS |
1550:
LPLSSSTSAP | TLAETMVVSA | HSLDKASHSS | TAGLGLSFCA | PSSSSSSGTA |
1600:
VSTSVSQPGM | VHPLVISSAV | VSTPGLPQPV | VPTSTPLLPQ | VPNIPPLVQP |
1650:
VVNVPAVQQT | LIHSQPQPAL | LPNQPHTHCP | EMDADTQSKA | PGIDDIKTLE |
1700:
EKLRSLFSEH | SSSGTQHASV | SLETPLVVET | TVTPGITTTA | VAPSKLMTST |
1750:
TSTCLPPTSL | PLGAAGMPVM | PVGTPGQVST | PGTHASAPVG | TATGVKPGTT |
1800:
PPKPTKTVVP | PVGTELSAGT | VPCEQLPPFP | GPSLIQSQQP | LEDLDAQLRR |
1850:
TLSPETITVA | PAVGPLSTMS | STTVTEAGTR | LQKDGTEGHV | TATSSGAGVV |
1900:
KMGRFQVSVT | MDDAQKERKN | RSEDTKSVHF | ESSTSESSVL | SSSSPESTLV |
1950:
KPEPNGISIS | GISLDVPDST | HKAPTPEAKS | DAGQPTKVGR | FQVTTTANKV |
2000:
GRFSVSRTED | KVTELKKEGP | VTSPPFRDSE | QTVIPAVIPK | KEKPELAEPS |
2050:
HLNGPSSDLE | AAFLSRGTED | GSGSPHSPPH | LCSKSLPVQN | LSQSLSNSFN |
2100:
SSYMSSDNES | DIEDEDLRLE | LRRLREKHLK | EIQDLQSRQK | HEIESLYTKL |
2150:
GKVPPAVIIP | PAAPLSGRRR | RPTKSKGSKS | SRSSSLGNKS | PQLSGNLSGQ |
2200:
SGTSVLHPQQ | TLHPAGNTPE | TGHNQLLQPL | KPSPSSDNLY | SAFTSDGAIS |
2250:
VPSLSAPGQG | TSSTNTVGGT | VSSQAAQAQP | PAMTSSRKGT | FTDDLHKLVD |
2300:
NWARDAMNLS | GRRGSKGHMN | YEGPGMARKF | SAPGQLCVPM | TSNLGGSTPI |
2350:
SAASATSLGH | FTKSMCPPQQ | YGFPPAPFGT | QWSGTGGPAP | QPLGQFQPVG |
2377:
TASLQNFNIS | NLQKSISNPP | GSNLRTT
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Pig
Human
Mouse
Rat
ELISA Kit for Mouse Serine/threonine-protein kinase WNK1
ELISA Kit for Mouse Serine/threonine-protein kinase WNK1
ELISA Kit for Mouse Serine/threonine-protein kinase WNK1
ELISA Kit for Mouse Serine/threonine-protein kinase WNK1
CLIA Kit for Mouse Serine/threonine-protein kinase WNK1
CLIA Kit for Mouse Serine/threonine-protein kinase WNK1
CLIA Kit for Mouse Serine/threonine-protein kinase WNK1
CLIA Kit for Mouse Serine/threonine-protein kinase WNK1
Polyclonal Antibody for Mouse Serine/threonine-protein kinase WNK1
Polyclonal Antibody for Mouse Serine/threonine-protein kinase WNK1
Polyclonal Antibody for Mouse Serine/threonine-protein kinase WNK1
Polyclonal Antibody for Mouse Serine/threonine-protein kinase WNK1
Monoclonal Antibody for Mouse Serine/threonine-protein kinase WNK1
Monoclonal Antibody for Mouse Serine/threonine-protein kinase WNK1
Monoclonal Antibody for Mouse Serine/threonine-protein kinase WNK1
Monoclonal Antibody for Mouse Serine/threonine-protein kinase WNK1
Protein for Mouse Serine/threonine-protein kinase WNK1
Protein for Mouse Serine/threonine-protein kinase WNK1
Protein for Mouse Serine/threonine-protein kinase WNK1
Protein for Mouse Serine/threonine-protein kinase WNK1
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;ALTERNATIVE SPLICING
strain :
C57BL/6 .
2.
"Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N.
,
Kikuno R.
,
Ohara R.
,
Inamoto S.
,
Koseki H.
,
Hiraoka S.
,
Saga Y.
,
Seino S.
,
Nishimura M.
,
Kaisho T.
,
Hoshino K.
,
Kitamura H.
,
Nagase T.
,
Ohara O.
,
Koga H.
DNA Res.11:205-218(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6)
tissue :
Embryonic tail .
3.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4 AND 5);PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2/3)
strain :
C57BL/6 .
tissue :
Embryo .
5.
"The transcriptional landscape of the mammalian genome."
Carninci P.
,
Kasukawa T.
,
Katayama S.
,
Gough J.
,
Frith M.C.
,
Maeda N.
,
Oyama R.
,
Ravasi T.
,
Lenhard B.
,
Wells C.
,
Kodzius R.
,
Shimokawa K.
,
Bajic V.B.
,
Brenner S.E.
,
Batalov S.
,
Forrest A.R.
,
Zavolan M.
,
Davis M.J.
,
Wilming L.G.
,
Aidinis V.
,
Allen J.E.
,
Ambesi-Impiombato A.
,
Apweiler R.
,
Aturaliya R.N.
,
Bailey T.L.
,
Bansal M.
,
Baxter L.
,
Beisel K.W.
,
Bersano T.
,
Bono H.
,
Chalk A.M.
,
Chiu K.P.
,
Choudhary V.
,
Christoffels A.
,
Clutterbuck D.R.
,
Crowe M.L.
,
Dalla E.
,
Dalrymple B.P.
,
de Bono B.
,
Della Gatta G.
,
di Bernardo D.
,
Down T.
,
Engstrom P.
,
Fagiolini M.
,
Faulkner G.
,
Fletcher C.F.
,
Fukushima T.
,
Furuno M.
,
Futaki S.
,
Gariboldi M.
,
Georgii-Hemming P.
,
Gingeras T.R.
,
Gojobori T.
,
Green R.E.
,
Gustincich S.
,
Harbers M.
,
Hayashi Y.
,
Hensch T.K.
,
Hirokawa N.
,
Hill D.
,
Huminiecki L.
,
Iacono M.
,
Ikeo K.
,
Iwama A.
,
Ishikawa T.
,
Jakt M.
,
Kanapin A.
,
Katoh M.
,
Kawasawa Y.
,
Kelso J.
,
Kitamura H.
,
Kitano H.
,
Kollias G.
,
Krishnan S.P.
,
Kruger A.
,
Kummerfeld S.K.
,
Kurochkin I.V.
,
Lareau L.F.
,
Lazarevic D.
,
Lipovich L.
,
Liu J.
,
Liuni S.
,
McWilliam S.
,
Madan Babu M.
,
Madera M.
,
Marchionni L.
,
Matsuda H.
,
Matsuzawa S.
,
Miki H.
,
Mignone F.
,
Miyake S.
,
Morris K.
,
Mottagui-Tabar S.
,
Mulder N.
,
Nakano N.
,
Nakauchi H.
,
Ng P.
,
Nilsson R.
,
Nishiguchi S.
,
Nishikawa S.
,
Nori F.
,
Ohara O.
,
Okazaki Y.
,
Orlando V.
,
Pang K.C.
,
Pavan W.J.
,
Pavesi G.
,
Pesole G.
,
Petrovsky N.
,
Piazza S.
,
Reed J.
,
Reid J.F.
,
Ring B.Z.
,
Ringwald M.
,
Rost B.
,
Ruan Y.
,
Salzberg S.L.
,
Sandelin A.
,
Schneider C.
,
Schoenbach C.
,
Sekiguchi K.
,
Semple C.A.
,
Seno S.
,
Sessa L.
,
Sheng Y.
,
Shibata Y.
,
Shimada H.
,
Shimada K.
,
Silva D.
,
Sinclair B.
,
Sperling S.
,
Stupka E.
,
Sugiura K.
,
Sultana R.
,
Takenaka Y.
,
Taki K.
,
Tammoja K.
,
Tan S.L.
,
Tang S.
,
Taylor M.S.
,
Tegner J.
,
Teichmann S.A.
,
Ueda H.R.
,
van Nimwegen E.
,
Verardo R.
,
Wei C.L.
,
Yagi K.
,
Yamanishi H.
,
Zabarovsky E.
,
Zhu S.
,
Zimmer A.
,
Hide W.
,
Bult C.
,
Grimmond S.M.
,
Teasdale R.D.
,
Liu E.T.
,
Brusic V.
,
Quackenbush J.
,
Wahlestedt C.
,
Mattick J.S.
,
Hume D.A.
,
Kai C.
,
Sasaki D.
,
Tomaru Y.
,
Fukuda S.
,
Kanamori-Katayama M.
,
Suzuki M.
,
Aoki J.
,
Arakawa T.
,
Iida J.
,
Imamura K.
,
Itoh M.
,
Kato T.
,
Kawaji H.
,
Kawagashira N.
,
Kawashima T.
,
Kojima M.
,
Kondo S.
,
Konno H.
,
Nakano K.
,
Ninomiya N.
,
Nishio T.
,
Okada M.
,
Plessy C.
,
Shibata K.
,
Shiraki T.
,
Suzuki S.
,
Tagami M.
,
Waki K.
,
Watahiki A.
,
Okamura-Oho Y.
,
Suzuki H.
,
Kawai J.
,
Hayashizaki Y.
more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-578
strain :
C57BL/6J .
tissue :
Embryo .
6.
"Human hypertension caused by mutations in WNK kinases."
Wilson F.H.
,
Disse-Nicodeme S.
,
Choate K.A.
,
Ishikawa K.
,
Nelson-Williams C.
,
Desitter I.
,
Gunel M.
,
Milford D.V.
,
Lipkin G.W.
,
Achard J.-M.
,
Feely M.P.
,
Dussol B.
,
Berland Y.
,
Unwin R.J.
,
Mayan H.
,
Simon D.B.
,
Farfel Z.
,
Jeunemaitre X.
,
Lifton R.P.
more...
Science293:1107-1112(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
8.
"Identification of a novel gene (HSN2) causing hereditary sensory and autonomic neuropathy type II through the study of Canadian genetic isolates."
Lafreniere R.G.
,
MacDonald M.L.E.
,
Dube M.-P.
,
MacFarlane J.
,
O'Driscoll M.
,
Brais B.
,
Meilleur S.
,
Brinkman R.R.
,
Dadivas O.
,
Pape T.
,
Platon C.
,
Radomski C.
,
Risler J.
,
Thompson J.
,
Guerra-Escobio A.-M.
,
Davar G.
,
Breakefield X.O.
,
Pimstone S.N.
,
Green R.
,
Pryse-Phillips W.
,
Goldberg Y.P.
,
Younghusband H.B.
,
Hayden M.R.
,
Sherrington R.
,
Rouleau G.A.
,
Samuels M.E.
more...
Am. J. Hum. Genet.74:1064-1073(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION OF THE HSN2 EXON
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2027;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
10.
"Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II."
Shekarabi M.
,
Girard N.
,
Riviere J.B.
,
Dion P.
,
Houle M.
,
Toulouse A.
,
Lafreniere R.G.
,
Vercauteren F.
,
Hince P.
,
Laganiere J.
,
Rochefort D.
,
Faivre L.
,
Samuels M.
,
Rouleau G.A.
J. Clin. Invest.118:2496-2505(2008)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ALTERNATIVE SPLICING (ISOFORMS 2 AND 3);TISSUE SPECIFICITY