WNT1 ELISA Kit for Human(Homo sapiens) | EIAab.comWNT1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > WNT1(Gene name) > Human

WNT1 (Gene name),

Proto-oncogene Wnt-1 (Protein name ), WNT1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

WNT1(INT1);

Protein name:

Proto-oncogene Wnt-1;

Alternative:

Proto-oncogene Int-1 homolog;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with PORCN. Interacts with RSPO1, RSPO2 and RSPO3 (By similarity). Interacts with WLS.

Function:

Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

370

Sequence:

50:

100:

150:

200:

250:

300:

350:

370:

WCCHVSCRNC | THTRVLHECL |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.248164

MIM:

164820

SMR:

P04628

KEGG:

hsa:7471

String:

P04628

Pfam:

PF00110

STRING:

9606.ENSP00000293549

Uniprot:

P04628

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ELISA Kit for Human Proto-oncogene Wnt-1

Cat.:

E1414h

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Packing:

96T

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ELISA Kit for Human Proto-oncogene Wnt-1

Cat.:

E1414c

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Packing:

96T

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ELISA Kit for Human Proto-oncogene Wnt-1

Cat.:

E1414m

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human Proto-oncogene Wnt-1

MSDS:

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CLIA Kit for Human Proto-oncogene Wnt-1

Cat.:

U1414h

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MSDS:

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Packing:

96T

CLIA Kit for Human Proto-oncogene Wnt-1

Cat.:

U1414m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Proto-oncogene Wnt-1

Cat.:

P1414Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Proto-oncogene Wnt-1

Cat.:

P1414Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Proto-oncogene Wnt-1

Protein for Human Proto-oncogene Wnt-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences."
van Ooyen A. , Kwee V. , Nusse R.
EMBO J.4:2905-2909(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Testis.
5.

"Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling."
Doubravska L. , Krausova M. , Gradl D. , Vojtechova M. , Tumova L. , Lukas J. , Valenta T. , Pospichalova V. , Fafilek B. , Plachy J. , Sebesta O. , Korinek V.
Cell. Signal.23:837-848(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY CYSTEINE PALMITOYLATION;PALMITOYLATION AT SER-224
6.

"Mutations in WNT1 cause different forms of bone fragility."
Keupp K. , Beleggia F. , Kayserili H. , Barnes A.M. , Steiner M. , Semler O. , Fischer B. , Yigit G. , Janda C.Y. , Becker J. , Breer S. , Altunoglu U. , Gruenhagen J. , Krawitz P. , Hecht J. , Schinke T. , Makareeva E. , Lausch E. , more...
Am. J. Hum. Genet.92:565-574(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INVOLVEMENT IN BMND16;VARIANTS OI15 CYS-177 AND CYS-298;VARIANT OSTEOP TRP-235;CHARACTERIZATION OF VARIANT OI15 CYS-177;CHARACTERIZATION OF VARIANT OSTEOP TRP-235
7.

"WNT1 mutations in early-onset osteoporosis and osteogenesis imperfecta."
Laine C.M. , Joeng K.S. , Campeau P.M. , Kiviranta R. , Tarkkonen K. , Grover M. , Lu J.T. , Pekkinen M. , Wessman M. , Heino T.J. , Nieminen-Pihala V. , Aronen M. , Laine T. , Kroeger H. , Cole W.G. , Lehesjoki A.E. , Nevarez L. , Krakow D. , more...
N. Engl. J. Med.368:1809-1816(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN OI15;VARIANT OSTEOP GLY-218;CHARACTERIZATION OF VARIANT OSTEOP GLY-218
8.

"WNT1 mutations in families affected by moderately severe and progressive recessive osteogenesis imperfecta."
Pyott S.M. , Tran T.T. , Leistritz D.F. , Pepin M.G. , Mendelsohn N.J. , Temme R.T. , Fernandez B.A. , Elsayed S.M. , Elsobky E. , Verma I. , Nair S. , Turner E.H. , Smith J.D. , Jarvik G.P. , Byers P.H.
Am. J. Hum. Genet.92:590-597(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT OI15 CYS-298
9.

"Mutations in WNT1 are a cause of osteogenesis imperfecta."
Fahiminiya S. , Majewski J. , Mort J. , Moffatt P. , Glorieux F.H. , Rauch F.
J. Med. Genet.50:345-348(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS OI15 PHE-143 AND PHE-355

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