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Index > Protein center > Wrnip1(Gene name) > Mouse
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  • Wrnip1 (Gene name),
  • ATPase WRNIP1 (Protein name ),  WRIP1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Wrnip1(Whip);
    Protein name:
    ATPase WRNIP1;
    Alternative:
    Werner helicase-interacting protein 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homooligomer; most likely an octamer. Interacts with POLD1, POLD2 an POLD4. Interacts (via UBZ-type zinc finger) with polyubiquitin (By similarity). Interacts with the N-terminal domain of WRN.
    Function:
    Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis.
    Subcellular Location:
    Nucleus Colocalizes with WRN in granular structures in the nucleus.
    Protein Attributes:
    Sequence length:
    660
    Sequence:
    50:
    MEVSGPEDDP | FLSQLHQVQC | PVCQQMMPAA | HINSHLDRCL | LLHPAGHAEP | 
    100:
    AAGSHRAGER | AKGPSPPGAK | RRRLSESSAL | KQPATPTAAE | SSEGEGEEGD | 
    150:
    DGGETESRES | YDAPPTPSGA | RLIPDFPVAR | SSSPARKGMG | KRPAAAAAAG | 
    200:
    SASPRSWDEA | EAQEEEEAGV | DGDGDADVDG | EDDPGHWDAD | AADASFGVSA | 
    250:
    GRAHPRALAA | EEIRQMLEGK | PLADKMRPDT | LQDYIGQSRA | VGQETLLRSL | 
    300:
    LEANEIPSLI | LWGPPGCGKT | TLAHIIANNS | KKHSIRFVTL | SATNAKTNDV | 
    350:
    RDVIKQAQNE | KSFFKRKTIL | FIDEIHRFNK | SQQDTFLPHV | ECGTITLIGA | 
    400:
    TTENPSFQVN | AALLSRCRVI | VLEKLPVEAM | VTILMRAINS | LGIHVLDSSR | 
    450:
    PTDPLSHSSN | CSSEPSVFIE | DKAVDTLAYL | SDGDARTGLN | GLQLAVLARL | 
    500:
    SSRKVFCKKS | GQTYSPSRVL | ITENDVKEGL | QRSHILYDRA | GEEHYNCISA | 
    550:
    LHKAMRGSDQ | NASLYWLARM | LEGGEDPLYV | ARRLVRFASE | DIGLADPSAL | 
    600:
    AQAVAAYQGC | HFIGMPECEV | LLAQCVVYFA | RAPKSIEVYS | AYNNVKACLR | 
    650:
    SHQGPLPPVP | LHLRNAPTRL | MKDLGYGKGY | KYNPMYSEPV | DQDYLPEELR | 
    660:
    GVDFFKQRRC | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ATPase WRNIP1
    ELISA Kit for Mouse ATPase WRNIP1
    ELISA Kit for Mouse ATPase WRNIP1
    CLIA Kit for Mouse ATPase WRNIP1
    CLIA Kit for Mouse ATPase WRNIP1
    CLIA Kit for Mouse ATPase WRNIP1
    Polyclonal Antibody for Mouse ATPase WRNIP1
    Polyclonal Antibody for Mouse ATPase WRNIP1
    Polyclonal Antibody for Mouse ATPase WRNIP1
    Monoclonal Antibody for Mouse ATPase WRNIP1
    Monoclonal Antibody for Mouse ATPase WRNIP1
    Monoclonal Antibody for Mouse ATPase WRNIP1
    Protein for Mouse ATPase WRNIP1
    Protein for Mouse ATPase WRNIP1
    Protein for Mouse ATPase WRNIP1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A novel protein interacts with the Werner's syndrome gene product physically and functionally."
      Kawabe Y. , Branzei D. , Hayashi T. , Suzuki H. , Masuko T. , Onoda F. , Heo S.-J. , Ikeda H. , Shimamoto A. , Furuichi Y. , Seki M. , Enomoto T.
      J. Biol. Chem.276:20364-20369(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH WRN;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      strain: C57BL/6.
      tissue: Testis.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6J.
      strain: NOD.
      tissue: Cerebellum.
      tissue: Liver.
      tissue: Placenta.
      tissue: Thymus.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: Czech II.
      strain: FVB/N-3.
      tissue: Mammary gland.
    5. 5.
      "Characterization of RuvB homologs in human and mouse."
      Shannon M. , Ramirez M. , Thelen M.P.
      Submitted (1999-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 182-660 (ISOFORM 1)
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-92;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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