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Index > Protein center > SLC7A11(Gene name) > Human
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  • SLC7A11 (Gene name),
  • Cystine/glutamate transporter (Protein name ),  XCT_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SLC7A11;
    Protein name:
    Cystine/glutamate transporter;
    Alternative:
    Calcium channel blocker resistance protein CCBR1;Amino acid transport system xc-;xCT;Solute carrier family 7 member 11;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Disulfide-linked heterodimer with the amino acid transport protein SLC3A2/4F2hc.
    Function:
    Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    501
    Sequence:
    50:
    MVRKPVVSTI | SKGGYLQGNV | NGRLPSLGNK | EPPGQEKVQL | KRKVTLLRGV | 
    100:
    SIIIGTIIGA | GIFISPKGVL | QNTGSVGMSL | TIWTVCGVLS | LFGALSYAEL | 
    150:
    GTTIKKSGGH | YTYILEVFGP | LPAFVRVWVE | LLIIRPAATA | VISLAFGRYI | 
    200:
    LEPFFIQCEI | PELAIKLITA | VGITVVMVLN | SMSVSWSARI | QIFLTFCKLT | 
    250:
    AILIIIVPGV | MQLIKGQTQN | FKDAFSGRDS | SITRLPLAFY | YGMYAYAGWF | 
    300:
    YLNFVTEEVE | NPEKTIPLAI | CISMAIVTIG | YVLTNVAYFT | TINAEELLLS | 
    350:
    NAVAVTFSER | LLGNFSLAVP | IFVALSCFGS | MNGGVFAVSR | LFYVASREGH | 
    400:
    LPEILSMIHV | RKHTPLPAVI | VLHPLTMIML | FSGDLDSLLN | FLSFARWLFI | 
    450:
    GLAVAGLIYL | RYKCPDMHRP | FKVPLFIPAL | FSFTCLFMVA | LSLYSDPFST | 
    500:
    GIGFVITLTG | VPAYYLFIIW | DKKPRWFRIM | SEKITRTLQI | ILEVVPEEDK | 
    501:
    L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    KEGG:
    UniGene:
    Pfam:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Cystine/glutamate transporter
    Cat.:
    E10985h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Cystine/glutamate transporter
    Cat.:
    E10985m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Cystine/glutamate transporter
    Cat.:
    U10985h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Cystine/glutamate transporter
    Cat.:
    U10985m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Cystine/glutamate transporter
    Cat.:
    P10985Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cystine/glutamate transporter
    Monoclonal Antibody for Human Cystine/glutamate transporter
    Monoclonal Antibody for Human Cystine/glutamate transporter
    Protein for Human Cystine/glutamate transporter
    Protein for Human Cystine/glutamate transporter

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Molecular cloning and expression of human xCT, the light chain of amino acid transport system xc-."
      Sato H. , Tamba M. , Kuriyama-Matsumura K. , Okuno S. , Bannai S.
      Antioxid. Redox Signal.2:665-671(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "CCBR1, novel CD98 light chain implicated in redox control and calcium signaling."
      Conklin D.S. , Beach D.H.
      Submitted (1999-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells."
      Bridges C.C. , Kekuda R. , Wang H. , Prasad P.D. , Mehta P. , Huang W. , Smith S.B. , Ganapathy V.
      Invest. Ophthalmol. Vis. Sci.42:47-54(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Placenta.
    4. 4.
      Borsani G. , Manzoni M. , Palacin M. , Pineda M. , Gasol E.
      Submitted (2002-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Tongue.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
    8. 8.
      "Membrane topology of system xc- light subunit reveals a re-entrant loop with substrate-restricted accessibility."
      Gasol E. , Jimenez-Vidal M. , Chillaron J. , Zorzano A. , Palacin M.
      J. Biol. Chem.279:31228-31236(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MEMBRANE TOPOLOGY;SUBCELLULAR LOCATION
    9. 9.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-26;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-26;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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