"Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance."
Torrents D. , Estevez R. , Pineda M. , Fernandez E. , Lloberas J. , Shi Y.-B. , Zorzano A. , Palacin M.
J. Biol. Chem.273:32437-32445(1998) [PubMed] [Europe PMC] [Abstract]

"Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family."
Pfeiffer R. , Rossier G. , Spindler B. , Meier C. , Kuehn L.C. , Verrey F.
EMBO J.18:49-57(1999) [PubMed] [Europe PMC] [Abstract]

"SLC7A7, encoding a putative permease-related protein, is mutated in patients with lysinuric protein intolerance."
Borsani G. , Bassi M.T. , Sperandeo M.P. , De Grandi A. , Buoninconti A. , Riboni M. , Manzoni M. , Incerti B. , Pepe A. , Andria G. , Ballabio A. , Sebastio G.
Nat. Genet.21:297-301(1999) [PubMed] [Europe PMC] [Abstract]

"SLC7A7 genomic structure and novel variants in three Japanese lysinuric protein intolerance families."
Noguchi A. , Shoji Y. , Koizumi A. , Takahashi T. , Shoji Y. , Matsumori M. , Kayo T. , Ohata T. , Wada Y. , Yoshimura I. , Maisawa S. , Konishi M. , Takasago Y. , Takada G.
Hum. Mutat.15:367-372(2000) [PubMed] [Europe PMC] [Abstract]

"Molecular and biological characterization of a novel monocyte amino acid permease, MOP-2."
Takayama K. , Yoshimoto M.
Submitted (1998-02) to the EMBL/GenBank/DDBJ databases

"Characterization of a human system y+L amino acid transporter."
Fukasawa Y. , Segawa H. , Endou H. , Kanai Y.
Submitted (1998-11) to the EMBL/GenBank/DDBJ databases

"Full-length cDNA libraries and normalization."
Li W.B. , Gruber C. , Jessee J. , Polayes D.
Submitted (2003-02) to the EMBL/GenBank/DDBJ databases

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , Yamamoto J. , Saito K. , Kawai Y. , Isono Y. , Nakamura Y. , Nagahari K. , Murakami K. , Yasuda T. , Iwayanagi T. , Wagatsuma M. , Shiratori A. , Sudo H. , Hosoiri T. , Kaku Y. , Kodaira H. , Kondo H. , Sugawara M. , Takahashi M. , Kanda K. , Yokoi T. , Furuya T. , Kikkawa E. , Omura Y. , Abe K. , Kamihara K. , Katsuta N. , Sato K. , Tanikawa M. , Yamazaki M. , Ninomiya K. , Ishibashi T. , Yamashita H. , Murakawa K. , Fujimori K. , Tanai H. , Kimata M. , Watanabe M. , Hiraoka S. , Chiba Y. , Ishida S. , Ono Y. , Takiguchi S. , Watanabe S. , Yosida M. , Hotuta T. , Kusano J. , Kanehori K. , Takahashi-Fujii A. , Hara H. , Tanase T.-O. , Nomura Y. , Togiya S. , Komai F. , Hara R. , Takeuchi K. , Arita M. , Imose N. , Musashino K. , Yuuki H. , Oshima A. , Sasaki N. , Aotsuka S. , Yoshikawa Y. , Matsunawa H. , Ichihara T. , Shiohata N. , Sano S. , Moriya S. , Momiyama H. , Satoh N. , Takami S. , Terashima Y. , Suzuki O. , Nakagawa S. , Senoh A. , Mizoguchi H. , Goto Y. , Shimizu F. , Wakebe H. , Hishigaki H. , Watanabe T. , Sugiyama A. , Takemoto M. , Kawakami B. , Yamazaki M. , Watanabe K. , Kumagai A. , Itakura S. , Fukuzumi Y. , Fujimori Y. , Komiyama M. , Tashiro H. , Tanigami A. , Fujiwara T. , Ono T. , Yamada K. , Fujii Y. , Ozaki K. , Hirao M. , Ohmori Y. , Kawabata A. , Hikiji T. , Kobatake N. , Inagaki H. , Ikema Y. , Okamoto S. , Okitani R. , Kawakami T. , Noguchi S. , Itoh T. , Shigeta K. , Senba T. , Matsumura K. , Nakajima Y. , Mizuno T. , Morinaga M. , Sasaki M. , Togashi T. , Oyama M. , Hata H. , Watanabe M. , Komatsu T. , Mizushima-Sugano J. , Satoh T. , Shirai Y. , Takahashi Y. , Nakagawa K. , Okumura K. , Nagase T. , Nomura N. , Kikuchi H. , Masuho Y. , Yamashita R. , Nakai K. , Yada T. , Nakamura Y. , Ohara O. , Isogai T. , Sugano S. more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , Yooseph S. , Lu F. , Nusskern D.R. , Shue B.C. , Zheng X.H. , Zhong F. , Delcher A.L. , Huson D.H. , Kravitz S.A. , Mouchard L. , Reinert K. , Remington K.A. , Clark A.G. , Waterman M.S. , Eichler E.E. , Adams M.D. , Hunkapiller M.W. , Myers E.W. , Venter J.C. more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Arginine transport through system y(+)L in cultured human fibroblasts: normal phenotype of cells from LPI subjects."
Dall'Asta V. , Bussolati O. , Sala R. , Rotoli B.M. , Sebastio G. , Sperandeo M.P. , Andria G. , Gazzola G.C.
Am. J. Physiol.279:C1829-C1837(2000) [PubMed] [Europe PMC] [Abstract]

"Two-way arginine transport in human endothelial cells: TNF-alpha stimulation is restricted to system y(+)."
Sala R. , Rotoli B.M. , Colla E. , Visigalli R. , Parolari A. , Bussolati O. , Gazzola G.C. , Dall'Asta V.
Am. J. Physiol.282:C134-C143(2002) [PubMed] [Europe PMC] [Abstract]

"Nitric oxide synthesis requires activity of the cationic and neutral amino acid transport system y+L in human umbilical vein endothelium."
Arancibia-Garavilla Y. , Toledo F. , Casanello P. , Sobrevia L.
Exp. Physiol.88:699-710(2003) [PubMed] [Europe PMC] [Abstract]

"INFgamma stimulates arginine transport through system y+L in human monocytes."
Rotoli B.M. , Bussolati O. , Sala R. , Barilli A. , Talarico E. , Gazzola G.C. , Dall'Asta V.
FEBS Lett.571:177-181(2004) [PubMed] [Europe PMC] [Abstract]

"Activation of classical protein kinase C decreases transport via systems y+ and y+L."
Rotmann A. , Simon A. , Martine U. , Habermeier A. , Closs E.I.
Am. J. Physiol.292:C2259-C2268(2007) [PubMed] [Europe PMC] [Abstract]

"Ornithine transport via cationic amino acid transporter-1 is involved in ornithine cytotoxicity in retinal pigment epithelial cells."
Kaneko S. , Ando A. , Okuda-Ashitaka E. , Maeda M. , Furuta K. , Suzuki M. , Matsumura M. , Ito S.
Invest. Ophthalmol. Vis. Sci.48:464-471(2007) [PubMed] [Europe PMC] [Abstract]

"Identification of SLC7A7, encoding y+LAT-1, as the lysinuric protein intolerance gene."
Torrents D. , Mykkaenen J. , Pineda M. , Feliubadalo L. , Estevez R. , de Cid R. , Sanjurjo P. , Zorzano A. , Nunes V. , Huoponen K. , Reinikainen A. , Simell O. , Savontaus M.-L. , Aula P. , Palacin M.
Nat. Genet.21:293-296(1999) [PubMed] [Europe PMC] [Abstract]

"Structure of the SLC7A7 gene and mutational analysis of patients affected by lysinuric protein intolerance."
Sperandeo M.P. , Bassi M.T. , Riboni M. , Parenti G. , Buoninconti A. , Manzoni M. , Incerti B. , Larocca M.R. , Di Rocco M. , Strisciuglio P. , Dianzani I. , Parini R. , Candito M. , Endo F. , Ballabio A. , Andria G. , Sebastio G. , Borsani G.
Am. J. Hum. Genet.66:92-99(2000) [PubMed] [Europe PMC] [Abstract]

"Functional analysis of novel mutations in y+LAT-1 amino acid transporter gene causing lysinuric protein intolerance (LPI)."
Mykkaenen J. , Torrents D. , Pineda M. , Camps M. , Yoldi M.E. , Horelli-Kuitunen N. , Huoponen K. , Heinonen M. , Oksanen J. , Simell O. , Savontaus M.-L. , Zorzano A. , Palacin M. , Aula P.
Hum. Mol. Genet.9:431-438(2000) [PubMed] [Europe PMC] [Abstract]

"Five novel SLC7A7 variants and y+L gene-expression pattern in cultured lymphoblasts from Japanese patients with lysinuric protein intolerance."
Shoji Y. , Noguchi A. , Shoji Y. , Matsumori M. , Takasago Y. , Takayanagi M. , Yoshida Y. , Ihara K. , Hara T. , Yamaguchi S. , Yoshino M. , Kaji M. , Yamamoto S. , Nakai A. , Koizumi A. , Hokezu Y. , Nagamatsu K. , Mikami H. , Kitajima I. , Takada G. more...
Hum. Mutat.20:375-381(2002) [PubMed] [Europe PMC] [Abstract]

"A y(+)LAT-1 mutant protein interferes with y(+)LAT-2 activity: implications for the molecular pathogenesis of lysinuric protein intolerance."
Sperandeo M.P. , Paladino S. , Maiuri L. , Maroupulos G.D. , Zurzolo C. , Taglialatela M. , Andria G. , Sebastio G.
Eur. J. Hum. Genet.13:628-634(2005) [PubMed] [Europe PMC] [Abstract]

"Lysinuric protein intolerance: identification and functional analysis of mutations of the SLC7A7 gene."
Sperandeo M.P. , Annunziata P. , Ammendola V. , Fiorito V. , Pepe A. , Soldovieri M.V. , Taglialatela M. , Andria G. , Sebastio G.
Hum. Mutat.25:410-410(2005) [PubMed] [Europe PMC] [Abstract]

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , Gazdar A.F. , Hartigan J. , Wu L. , Liu C. , Parmigiani G. , Park B.H. , Bachman K.E. , Papadopoulos N. , Vogelstein B. , Kinzler K.W. , Velculescu V.E. more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

"Lysinuric protein intolerance: update and extended mutation analysis of the SLC7A7 gene."
Sperandeo M.P. , Andria G. , Sebastio G.
Hum. Mutat.29:14-21(2008) [PubMed] [Europe PMC] [Abstract]