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Index > Protein center > Slc7a6(Gene name) > Mouse
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  • Slc7a6 (Gene name),
  • Y+L amino acid transporter 2 (Protein name ),  YLAT2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc7a6(Kiaa0245);
    Protein name:
    Y+L amino acid transporter 2;
    Alternative:
    y(+)L-type amino acid transporter 2(Y+LAT2;y+LAT-2);Solute carrier family 7 member 6;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Disulfide-linked heterodimer with the amino acid transport protein SLC3A2/4F2hc.
    Function:
    Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires co-expression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial cells.
    Subcellular Location:
    Basolateral cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    515
    Sequence:
    50:
    MEAQELGSPT | PTYHLLPKAN | QHTVKEDAGS | PSQGSPETMQ | LKKEISLLNG | 
    100:
    VSLVVGNMIG | SGIFVSPKGV | LKYTASYGLS | LIVWAIGGLF | SVVGALCYAE | 
    150:
    LGTTITKSGA | SYAYILEAFG | GFIAFIRLWV | SLLIVEPTSQ | AIIAITFANY | 
    200:
    IIKPSFPTCD | PPYVACRLLA | AACVCLLTFV | NCAYVKWGTR | VQDTFTYAKV | 
    250:
    LALIAIIIMG | LVKLCQGHTE | HFQDAFKGSS | WNVGDLSLAL | YSALFSYSGW | 
    300:
    DTLNFVTEEI | KNPERNLPLA | IGISMPIVTL | IYILTNVAYY | TVLNIQDVHK | 
    350:
    SDAVAVTFAD | QTFGMFSWTI | PIAVALSCFG | GLNASIFASS | RLFFVGSREG | 
    400:
    HLPNLLSMIH | IERFTPVPAL | LFNCTMTLIY | LVVKDVFLLI | NYFSFSYWFF | 
    450:
    VGLSVVGQLY | LRWKEPDWPR | PLKLSLFFPI | VFCVCSLFLV | AVPLFSDTIN | 
    500:
    SLIGIGIALS | GVPVYFLGVY | LPESRRPLFI | RNVLATVTRV | TQKLCFCVLT | 
    515:
    ELDVTEEKNV | ERKTD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    Pfam:
    UniGene:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Y+L amino acid transporter 2
    ELISA Kit for Mouse Y+L amino acid transporter 2
    CLIA Kit for Mouse Y+L amino acid transporter 2
    CLIA Kit for Mouse Y+L amino acid transporter 2
    Polyclonal Antibody for Mouse Y+L amino acid transporter 2
    Polyclonal Antibody for Mouse Y+L amino acid transporter 2
    Monoclonal Antibody for Mouse Y+L amino acid transporter 2
    Monoclonal Antibody for Mouse Y+L amino acid transporter 2
    Protein for Mouse Y+L amino acid transporter 2
    Protein for Mouse Y+L amino acid transporter 2

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Embryonic tail.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      strain: NOD.
      tissue: Embryo.
      tissue: Embryonic stem cell.
      tissue: Embryonic stomach.
      tissue: Eye.
      tissue: Lung.
      tissue: Spleen.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: FVB/N.
      tissue: Mammary tumor.
    4. 4.
      "The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine."
      Broeer A. , Wagner C.A. , Lang F. , Broeer S.
      Biochem. J.349:787-795(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 140-293 (ISOFORM 1);TISSUE SPECIFICITY
    5. 5.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-30;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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