IL-2 (interleuin-2) is a kind of Interleukin, mainly produced by T cells or T cell lines. It is a type of cell growth factor in the immune system. It can regulate the activity of white blood cells in the immune system, promote the proliferation of Th0 and CTL. It participates in antibody response and the moderation of haematogenesis function. It also plays an important role in oncological surveillance.
IL-2 is part of the body's natural response to microbial infection, IL-2 mediates its effects by binding to IL-2 receptors, which is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes. IL-2R consist of three chains : α(also called IL-2Rα, CD25, or Tac antigen), β (also called IL-2Rβ, or CD122), and γ (also called IL-2Rγ, γc, common gamma chain, or CD132).
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