[Sign in] [Register]   

EIAab logo

EIAab news detail, please contact if you have any questions about online orders and payment.
Investigation of lectin complement proteins in urinary schistosomiasis and visceral leishmaniasis
Update time:2016-07-27 23:34:02   【 Font: Large  Medium Small


Complement lectins are pathogen recognition receptors (PRRs) that bind to pathogen associated molecular patterns (PAMPs) of various microbes. The circulating serum levels and functional genetic variants of four such innate immune recognition elements, namely the human mannose-binding lectin (MBL), ficolin-2 (FCN2), collectin 11 (CL-K1), mannose-binding associated serine protease-2 (MASP2) were studied in intracellular (visceral leishmaniasis) and extracellular (urinary schistosomiasis) parasitic diseases. In extracellular Schistosoma haematobium infection, MBL, MASP2, and collectin-11 (CL-K1) and their functional variants were associated with relative protection. In intra-cellular Leishmania donovani infection, MBL, ficolin-2 and their functional variants were observed to be a susceptible host factor. IL-6 was observed to regulate the lectin expression during distinct parasitic infections. In conclusion, this dissertation provides probable evidence on the differential role of lectins in intra and extracellular infections.

Cited products
Source:Universit?t Tübingen      by Selvaraj J A.
Hot Genes
ALCAM ACE KSR2 ASPRO C19orf80 Gdf5 Trap1a Atf2
Top Searches
Ubiquitin ELISA Ubiquitin-protein ligase metalloproteinase Asprosin Tumor necrosis TRAP1A vitamin d
Why choose EIAAB
Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
Further Information
About us Protein center Bank account Distributors Terms & Conditions Career

Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab